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• W2023502475 endingPage "470" @default.
• W2023502475 startingPage "465" @default.
• W2023502475 abstract "Endocrine dysfunctions have been increasingly recognized following traumatic brain injury. Ever more numerous studies on acute head-injured adults have also raised concern about this risk in children and adolescents who have experienced head injury. The current review of the pediatric literature summarizes recent findings on acute-phase dysfunction and traumatic brain injury-associated hypopituitarism.The pathophysiologic mechanisms underlying acute-phase hyponatremic and hypernatremic disorders have been elucidated. Prospective studies on traumatic brain injury-associated hypopituitarism in pediatric patients are ongoing and preliminary data are available.Traumatic brain injury, a 'silent epidemic' that carries a considerable burden of disabilities, leads to a variety of endocrine dysfunctions in 28-69% of adult acute head-injured patients. In the acute posttraumatic phase, adrenal insufficiency and electrolyte disorders are critical conditions. Neurosurgical patients, particularly those prone to neurological damage, require prompt diagnosis. Hypopituitarism may be diagnosed months or years after a traumatic brain injury event. Since growth hormone and gonadotropin secretion are most frequently compromised, careful follow-up of growth and pubertal development is mandatory in children hospitalized for traumatic brain injury." @default.
• W2023502475 created "2016-06-24" @default.
• W2023502475 creator A5068355215 @default.
• W2023502475 creator A5074731347 @default.
• W2023502475 date "2007-08-01" @default.
• W2023502475 modified "2023-10-12" @default.
• W2023502475 title "The effects of head trauma on hypothalamic–pituitary function in children and adolescents" @default.
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• W2023502475 doi "https://doi.org/10.1097/mop.0b013e3281ab6eeb" @default.
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• W2023502475 hasPublicationYear "2007" @default.
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