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- W2023504014 abstract "The pharmacokinetics of ketoprofen were studied in 7 volunteers and in 5 patients suffering from varying degrees of renal insufficiency. All the subjects received a single oral dose (50 mg) of ketoprofen. Plasma concentrations were measured up to 24 hours after administration and urinary excretion for 2 days. Ketoprofen concentrations were determined by mass-fragmentography with a minimum level of detection of 0.02 mg/1. As expected, a reduction of the [51Cr]EDTA clearance was correlated with an increase in the elimination half-life of ketoprofen. The urinary excretion corresponded to results reported by other groups." @default.
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- W2023504014 date "1981-01-01" @default.
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- W2023504014 title "Pharmacokinetics of Ketoprofen in Patients with Chronic Renal Failure" @default.
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- W2023504014 doi "https://doi.org/10.3109/03009748109095297" @default.
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