FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023505524> ?p ?o ?g. }

• W2023505524 endingPage "755" @default.
• W2023505524 startingPage "743" @default.
• W2023505524 abstract "Antibiotic treatment failure contributes to the economic and humanistic burdens of community-acquired pneumonia (CAP) by increasing morbidity, mortality, and healthcare costs. This study compared treatment failure rates of levofloxacin with those of other antibiotics in a large US sample.Medical and pharmacy claims in the nationally representative SDI database were used to identify adults with a new outpatient diagnosis of CAP receiving a study antibiotic (levofloxacin, amoxicillin/clavulanate, azithromycin, moxifloxacin) between September 1, 2005 and March 31, 2008. Treatment failure was defined as ≥1 of the following events ≤30 days after index date: a refill for the index antibiotic after completed days of therapy, a different antibiotic dispensed >1 day after the index prescription, or hospitalization with a pneumonia diagnosis or emergency department visit >3 days postindex. Cohorts were propensity score matched for demographic and clinical characteristics. Treatment failure rates were compared between pairs of cohorts for the full sample and for high-risk patients (age ≥65 and/or on Medicaid).Among the 3994 study patients, the numbers of dispensed index prescriptions were 268 for amoxicillin/clavulanate, 1609 for azithromycin, 1460 for levofloxacin, and 657 for moxifloxacin. Unadjusted treatment failure rates for the sample were 20.8% for levofloxacin, 23.9% for amoxicillin/clavulanate, 23.9% for azithromycin, and 19.9% for moxifloxacin. For high-risk patients, unadjusted treatment failure rates were 19.1% for levofloxacin, 26.1% for amoxicillin/clavulanate, 26.3% for azithromycin, and 24.3% for moxifloxacin. Propensity score-matched treatment failure rates were significantly lower with levofloxacin than azithromycin (19.8% vs. 24.5%, odds ratio [OR] comparator vs. levofloxacin 1.38; 95% CI: 1.14, 1.67), a difference amplified in high-risk patients (19.0% vs. 26.4%, OR 1.61; 95% CI: 1.22, 2.13). No significant differences were observed for other paired comparisons.In a large US sample, treatment failure in CAP appeared to be less likely with quinolones (such as levofloxacin) than azithromycin, an effect particularly marked in high-risk patients (age ≥65 and/or on Medicaid)." @default.
• W2023505524 created "2016-06-24" @default.
• W2023505524 creator A5004154463 @default.
• W2023505524 creator A5004354044 @default.
• W2023505524 creator A5005458541 @default.
• W2023505524 creator A5012212211 @default.
• W2023505524 creator A5020500436 @default.
• W2023505524 creator A5033435340 @default.
• W2023505524 creator A5075820036 @default.
• W2023505524 date "2010-08-26" @default.
• W2023505524 modified "2023-10-06" @default.
• W2023505524 title "Comparative antibiotic failure rates in the treatment of community-acquired pneumonia: Results from a claims analysis" @default.
• W2023505524 cites W1851941135 @default.
• W2023505524 cites W1967342049 @default.
• W2023505524 cites W1977836560 @default.
• W2023505524 cites W1981332539 @default.
• W2023505524 cites W1985792676 @default.
• W2023505524 cites W1988941701 @default.
• W2023505524 cites W1989983346 @default.
• W2023505524 cites W1994201397 @default.
• W2023505524 cites W2026932543 @default.
• W2023505524 cites W2036438086 @default.
• W2023505524 cites W2051380573 @default.
• W2023505524 cites W2064213918 @default.
• W2023505524 cites W2092974798 @default.
• W2023505524 cites W2109592882 @default.
• W2023505524 cites W2127416963 @default.
• W2023505524 cites W2149062621 @default.
• W2023505524 cites W2154870928 @default.
• W2023505524 cites W4232594334 @default.
• W2023505524 cites W4236249820 @default.
• W2023505524 doi "https://doi.org/10.1007/s12325-010-0062-1" @default.
• W2023505524 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7090925" @default.
• W2023505524 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20799007" @default.
• W2023505524 hasPublicationYear "2010" @default.
• W2023505524 type Work @default.
• W2023505524 sameAs 2023505524 @default.
• W2023505524 citedByCount "19" @default.
• W2023505524 countsByYear W20235055242012 @default.
• W2023505524 countsByYear W20235055242014 @default.
• W2023505524 countsByYear W20235055242015 @default.
• W2023505524 countsByYear W20235055242016 @default.
• W2023505524 countsByYear W20235055242017 @default.
• W2023505524 countsByYear W20235055242018 @default.
• W2023505524 countsByYear W20235055242019 @default.
• W2023505524 countsByYear W20235055242020 @default.
• W2023505524 countsByYear W20235055242021 @default.
• W2023505524 countsByYear W20235055242022 @default.
• W2023505524 crossrefType "journal-article" @default.
• W2023505524 hasAuthorship W2023505524A5004154463 @default.
• W2023505524 hasAuthorship W2023505524A5004354044 @default.
• W2023505524 hasAuthorship W2023505524A5005458541 @default.
• W2023505524 hasAuthorship W2023505524A5012212211 @default.
• W2023505524 hasAuthorship W2023505524A5020500436 @default.
• W2023505524 hasAuthorship W2023505524A5033435340 @default.
• W2023505524 hasAuthorship W2023505524A5075820036 @default.
• W2023505524 hasBestOaLocation W20235055242 @default.
• W2023505524 hasConcept C126322002 @default.
• W2023505524 hasConcept C2426938 @default.
• W2023505524 hasConcept C2776102371 @default.
• W2023505524 hasConcept C2777914695 @default.
• W2023505524 hasConcept C2778314733 @default.
• W2023505524 hasConcept C2778836808 @default.
• W2023505524 hasConcept C2778907293 @default.
• W2023505524 hasConcept C2779708577 @default.
• W2023505524 hasConcept C2781276175 @default.
• W2023505524 hasConcept C501593827 @default.
• W2023505524 hasConcept C71924100 @default.
• W2023505524 hasConcept C86803240 @default.
• W2023505524 hasConcept C89423630 @default.
• W2023505524 hasConcept C98274493 @default.
• W2023505524 hasConceptScore W2023505524C126322002 @default.
• W2023505524 hasConceptScore W2023505524C2426938 @default.
• W2023505524 hasConceptScore W2023505524C2776102371 @default.
• W2023505524 hasConceptScore W2023505524C2777914695 @default.
• W2023505524 hasConceptScore W2023505524C2778314733 @default.
• W2023505524 hasConceptScore W2023505524C2778836808 @default.
• W2023505524 hasConceptScore W2023505524C2778907293 @default.
• W2023505524 hasConceptScore W2023505524C2779708577 @default.
• W2023505524 hasConceptScore W2023505524C2781276175 @default.
• W2023505524 hasConceptScore W2023505524C501593827 @default.
• W2023505524 hasConceptScore W2023505524C71924100 @default.
• W2023505524 hasConceptScore W2023505524C86803240 @default.
• W2023505524 hasConceptScore W2023505524C89423630 @default.
• W2023505524 hasConceptScore W2023505524C98274493 @default.
• W2023505524 hasIssue "10" @default.
• W2023505524 hasLocation W20235055241 @default.
• W2023505524 hasLocation W20235055242 @default.
• W2023505524 hasLocation W20235055243 @default.
• W2023505524 hasLocation W20235055244 @default.
• W2023505524 hasOpenAccess W2023505524 @default.
• W2023505524 hasPrimaryLocation W20235055241 @default.
• W2023505524 hasRelatedWork W1564014304 @default.
• W2023505524 hasRelatedWork W1924200820 @default.
• W2023505524 hasRelatedWork W1988039140 @default.
• W2023505524 hasRelatedWork W2365763310 @default.
• W2023505524 hasRelatedWork W2381717832 @default.
• W2023505524 hasRelatedWork W2394455607 @default.

• next