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- W2023506144 abstract "The kidneys play the crucial role in the maintenance of the body fluid volume homeostasis. Several hypotheses have been introduced to explain sodium and water retention leading to edematous states in such pathologic conditions as congestive heart failure (CHF) and cirrhosis. We have suggested a unifying arterial underfilling hypothesis, explaining the development of edema in these conditions. Arterial underfilling, caused by decreased cardiac output or peripheral arterial vasodilation, leads to activation of the sympathetic nervous system, renin-angiotensin-aldosterone system, and nonosmotic vasopressin release. This review discusses the pathophysiologic mechanisms resulting in renal sodium and water retention, impaired mineralocorticoid escape, and resistance to atrial natriuretic peptide in patients with CHF and cirrhosis. Furthermore, the basis of current therapies in these disorders is discussed, including beta-blockers, angiotensin-converting enzyme inhibitors, angiotensin-receptor blockers, aldosterone antagonists, and diuretics in CHF and cirrhosis, as well as new approaches to treatment of water retention with vasopressin V(2) receptor antagonists." @default.
- W2023506144 created "2016-06-24" @default.
- W2023506144 creator A5009700893 @default.
- W2023506144 creator A5037135283 @default.
- W2023506144 creator A5088279175 @default.
- W2023506144 date "2001-03-01" @default.
- W2023506144 modified "2023-10-16" @default.
- W2023506144 title "Pathogenesis and management of sodium and water retention in cardiac failure and cirrhosis" @default.
- W2023506144 cites W100854703 @default.
- W2023506144 cites W12599985 @default.
- W2023506144 cites W1493544519 @default.
- W2023506144 cites W1548704948 @default.
- W2023506144 cites W1670033039 @default.
- W2023506144 cites W1674514490 @default.
- W2023506144 cites W171291507 @default.
- W2023506144 cites W1727785519 @default.
- W2023506144 cites W176563160 @default.
- W2023506144 cites W177039186 @default.
- W2023506144 cites W180946569 @default.
- W2023506144 cites W1859131610 @default.
- W2023506144 cites W1944772484 @default.
- W2023506144 cites W1954488069 @default.
- W2023506144 cites W1963570371 @default.
- W2023506144 cites W1967056108 @default.
- W2023506144 cites W1967340565 @default.
- W2023506144 cites W1968129466 @default.
- W2023506144 cites W1970444261 @default.
- W2023506144 cites W1973376522 @default.
- W2023506144 cites W1978685662 @default.
- W2023506144 cites W1981910968 @default.
- W2023506144 cites W1981972230 @default.
- W2023506144 cites W1985453872 @default.
- W2023506144 cites W1987981002 @default.
- W2023506144 cites W1988215184 @default.
- W2023506144 cites W1997077374 @default.
- W2023506144 cites W1997636220 @default.
- W2023506144 cites W1999322668 @default.
- W2023506144 cites W1999487197 @default.
- W2023506144 cites W2002866895 @default.
- W2023506144 cites W2003342097 @default.
- W2023506144 cites W2004794332 @default.
- W2023506144 cites W2005781144 @default.
- W2023506144 cites W2008713440 @default.
- W2023506144 cites W2009114046 @default.
- W2023506144 cites W2011217156 @default.
- W2023506144 cites W2013712391 @default.
- W2023506144 cites W2015816231 @default.
- W2023506144 cites W2016252006 @default.
- W2023506144 cites W2016532277 @default.
- W2023506144 cites W2019820914 @default.
- W2023506144 cites W2020618573 @default.
- W2023506144 cites W2022128836 @default.
- W2023506144 cites W2022241368 @default.
- W2023506144 cites W2022458854 @default.
- W2023506144 cites W2025543329 @default.
- W2023506144 cites W2026467922 @default.
- W2023506144 cites W2027206878 @default.
- W2023506144 cites W2027406407 @default.
- W2023506144 cites W2028078450 @default.
- W2023506144 cites W2029126830 @default.
- W2023506144 cites W2029414689 @default.
- W2023506144 cites W2031118908 @default.
- W2023506144 cites W2032011368 @default.
- W2023506144 cites W2032497942 @default.
- W2023506144 cites W2035376123 @default.
- W2023506144 cites W2036563539 @default.
- W2023506144 cites W2037749453 @default.
- W2023506144 cites W2040815912 @default.
- W2023506144 cites W2040960119 @default.
- W2023506144 cites W2041508296 @default.
- W2023506144 cites W2043100266 @default.
- W2023506144 cites W2045019226 @default.
- W2023506144 cites W2046891147 @default.
- W2023506144 cites W2049215784 @default.
- W2023506144 cites W2050062145 @default.
- W2023506144 cites W2051060089 @default.
- W2023506144 cites W2052097767 @default.
- W2023506144 cites W2054641887 @default.
- W2023506144 cites W2055329932 @default.
- W2023506144 cites W2056672308 @default.
- W2023506144 cites W2056695599 @default.
- W2023506144 cites W2057640040 @default.
- W2023506144 cites W2066104567 @default.
- W2023506144 cites W2066609913 @default.
- W2023506144 cites W2067187990 @default.
- W2023506144 cites W2068963713 @default.
- W2023506144 cites W2071437372 @default.
- W2023506144 cites W2071513511 @default.
- W2023506144 cites W2072646675 @default.
- W2023506144 cites W2078113157 @default.
- W2023506144 cites W2081550182 @default.
- W2023506144 cites W2081714973 @default.
- W2023506144 cites W2083616382 @default.
- W2023506144 cites W2086075288 @default.
- W2023506144 cites W2086266014 @default.
- W2023506144 cites W2086276564 @default.
- W2023506144 cites W2086382158 @default.
- W2023506144 cites W2087450723 @default.