Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023507949> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2023507949 endingPage "794" @default.
- W2023507949 startingPage "793" @default.
- W2023507949 abstract "<h3>Objectives</h3> The Outcome Measures in Rheumatology Initiative established the Contextual Factors Working Group to guide the understanding, identification and handling of contextual factors for clinical trials. In clinical research, different uses of the term ‘contextual factors’ exist. This study explores the perspectives of researchers (including clinicians) and patients in defining 9contextual factor’ and its related terminology, identifying such factors and accounting for them in trials across rheumatology. <h3>Methods</h3> We conducted individual semistructured interviews with researchers (including clinicians) who have experience within the field of contextual factors in clinical trials or other potentially relevant areas, and small focus group interviews with patients with rheumatic conditions. We transcribed the interviews and applied qualitative content analysis. <h3>Results</h3> We interviewed 12 researchers and 7 patients. Researcher9s and patient9s descriptions of contextual factors were categorised into two broad themes, each comprising two contextual factors types. The ‘treatment effect’ theme focused on factors explaining variations in treatment effects (A) among patients and (B) among studies. The ‘outcome measurement’ theme focused on factors that explain (C) variations in the measurement result itself (apart from actual changes/differences in the outcome) and (D) variations in the outcome itself (beside treatment of interest). Methods for identifying and handling contextual factors differed among these themes and types. <h3>Conclusions</h3> Two main themes for contextual factors with four types of contextual factors were identified based on input from researchers and patients. This will guide operationalisation of contextual factors. Further research should refine our findings and establish consensus among relevant stakeholders." @default.
- W2023507949 created "2016-06-24" @default.
- W2023507949 creator A5008205425 @default.
- W2023507949 date "2008-06-01" @default.
- W2023507949 modified "2023-09-27" @default.
- W2023507949 title "Circulating progenitor cells in coronary heart disease" @default.
- W2023507949 cites W1974815597 @default.
- W2023507949 cites W2153555435 @default.
- W2023507949 doi "https://doi.org/10.1136/hrt.2008.141812" @default.
- W2023507949 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18480353" @default.
- W2023507949 hasPublicationYear "2008" @default.
- W2023507949 type Work @default.
- W2023507949 sameAs 2023507949 @default.
- W2023507949 citedByCount "2" @default.
- W2023507949 countsByYear W20235079492012 @default.
- W2023507949 crossrefType "journal-article" @default.
- W2023507949 hasAuthorship W2023507949A5008205425 @default.
- W2023507949 hasConcept C126322002 @default.
- W2023507949 hasConcept C138885662 @default.
- W2023507949 hasConcept C144024400 @default.
- W2023507949 hasConcept C151730666 @default.
- W2023507949 hasConcept C190248442 @default.
- W2023507949 hasConcept C2779343474 @default.
- W2023507949 hasConcept C2781238097 @default.
- W2023507949 hasConcept C36289849 @default.
- W2023507949 hasConcept C41895202 @default.
- W2023507949 hasConcept C512399662 @default.
- W2023507949 hasConcept C535046627 @default.
- W2023507949 hasConcept C547195049 @default.
- W2023507949 hasConcept C71611378 @default.
- W2023507949 hasConcept C71924100 @default.
- W2023507949 hasConcept C86803240 @default.
- W2023507949 hasConceptScore W2023507949C126322002 @default.
- W2023507949 hasConceptScore W2023507949C138885662 @default.
- W2023507949 hasConceptScore W2023507949C144024400 @default.
- W2023507949 hasConceptScore W2023507949C151730666 @default.
- W2023507949 hasConceptScore W2023507949C190248442 @default.
- W2023507949 hasConceptScore W2023507949C2779343474 @default.
- W2023507949 hasConceptScore W2023507949C2781238097 @default.
- W2023507949 hasConceptScore W2023507949C36289849 @default.
- W2023507949 hasConceptScore W2023507949C41895202 @default.
- W2023507949 hasConceptScore W2023507949C512399662 @default.
- W2023507949 hasConceptScore W2023507949C535046627 @default.
- W2023507949 hasConceptScore W2023507949C547195049 @default.
- W2023507949 hasConceptScore W2023507949C71611378 @default.
- W2023507949 hasConceptScore W2023507949C71924100 @default.
- W2023507949 hasConceptScore W2023507949C86803240 @default.
- W2023507949 hasIssue "6" @default.
- W2023507949 hasLocation W20235079491 @default.
- W2023507949 hasLocation W20235079492 @default.
- W2023507949 hasLocation W20235079493 @default.
- W2023507949 hasOpenAccess W2023507949 @default.
- W2023507949 hasPrimaryLocation W20235079491 @default.
- W2023507949 hasRelatedWork W1495287984 @default.
- W2023507949 hasRelatedWork W1557809428 @default.
- W2023507949 hasRelatedWork W2337969177 @default.
- W2023507949 hasRelatedWork W2919534039 @default.
- W2023507949 hasRelatedWork W2945643062 @default.
- W2023507949 hasRelatedWork W4206807087 @default.
- W2023507949 hasRelatedWork W4319304541 @default.
- W2023507949 hasRelatedWork W612572718 @default.
- W2023507949 hasRelatedWork W2248324540 @default.
- W2023507949 hasRelatedWork W3254890 @default.
- W2023507949 hasVolume "94" @default.
- W2023507949 isParatext "false" @default.
- W2023507949 isRetracted "false" @default.
- W2023507949 magId "2023507949" @default.
- W2023507949 workType "article" @default.