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- W2023508675 abstract "Early phase pharmaceutical research compounds must be fully characterized in order to have confidence in any testing results. Traditional methods such as HPLC/MS do not give any indication of counterion presence or identity for many common counterions such as trifluoroacetate, acetate, or succinate. Herein, we describe a combined approach of ion chromatography and quantitative nuclear magnetic resonance spectroscopy in order to identify and quantify counterions in research samples of limited quantity. Forty-two research samples were analyzed and compared for trifluoroacetate, acetate, and succinate salts." @default.
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- W2023508675 date "2014-03-11" @default.
- W2023508675 modified "2023-09-26" @default.
- W2023508675 title "A COMBINED APPROACH OF ION CHROMATOGRAPHY AND QUANTITATIVE NMR TO ACCURATELY DETERMINE COUNTERION STOICHIOMETRY" @default.
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- W2023508675 doi "https://doi.org/10.1080/10826076.2013.794739" @default.
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