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- W2023509263 abstract "Human glycodelin, a lipocalin with a high amino acid similarity to beta-lactoglobulins, appears as various glycoforms with different biological activities in endometrium (glycodelin-A) and seminal plasma (glycodelin-S). We found that the structures of these glycodelins and beta-lactoglobulin are similar. Despite this structural similarity, unlike beta-lactoglobulin, glycodelin-A binds neither retinoic acid nor retinol. It was impossible to detect any endogenous retinoids or steroids in any of the two purified glycodelins. Both their glycoforms share similar thermodynamic parameters of reversible denaturation suggesting that native folding of glycodelin-A and glycodelin-S is not influenced by the differences in glycosylation or by ligand binding." @default.
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- W2023509263 date "1999-04-30" @default.
- W2023509263 modified "2023-10-16" @default.
- W2023509263 title "Glycodelin and β-lactoglobulin, lipocalins with a high structural similarity, differ in ligand binding properties" @default.
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- W2023509263 doi "https://doi.org/10.1016/s0014-5793(99)00490-1" @default.
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