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- W2023509941 abstract "Sendai virosomes can deliver encapsulated contents into the cytoplasm directly in a virus fusion-dependent manner. In this paper, Sendai virosomes-formulated melanoma vaccine was constructed and its anti-tumor effects were investigated. The melanoma vaccine was prepared by encapsulating mixture antigen into the Sendai virosomes. The antigen, mixture proteins were extracted from B16 melanoma cells. The cytotoxic T lymphocyte (CTL) response level was evaluated by 51Cr release method, and the change of CD4+ and CD8+ expression as well as the concentration of IgG in serum of immunized mice was measured. The results showed that Sendai virosomes-formulated melanoma vaccine can effectively elicit not only systemic immune response but also strong CTL response. Sendai virosomes can be used as an effective vector for use in anti-tumor vaccine therapy." @default.
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- W2023509941 date "2007-02-01" @default.
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- W2023509941 title "Enhanced immune responses induced by vaccine using Sendai virosomes as carrier" @default.
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- W2023509941 doi "https://doi.org/10.1016/j.ijpharm.2006.08.033" @default.
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