Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023514819> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2023514819 endingPage "162" @default.
- W2023514819 startingPage "158" @default.
- W2023514819 abstract "A sensitive and specific ultra-performance liquid chromatography tandem mass spectrometry (LC-MS/MS) method has been developed for the determination of nicousamide in human plasma. This method has also been validated in terms of selectivity, linearity, lower limit of quantification (LLOQ), accuracy, precision, stability, matrix effect and recovery. Chromatography was carried out on an Acquity UPLC CSH C18 column and mass spectrometric analysis was performed using an QTrap5500 mass spectrometer coupled with electro-spray ionization (ESI) source in the Negative ion mode. The MRM transition of m/z 399→353 was used to quantify nicousamide. The assay was validated from 1 to 1000 ng/mL for nicousamide. Intra- and Inter-day precision for nicousamide was <13.1%, method accuracy (RE%) was between -7.5 and 8.8%. This method was used to support a clinical study where a single oral dose was administered by Chinese healthy volunteers to investigate the pharmacokinetics of nicousamide." @default.
- W2023514819 created "2016-06-24" @default.
- W2023514819 creator A5002891743 @default.
- W2023514819 creator A5024827414 @default.
- W2023514819 creator A5064307000 @default.
- W2023514819 creator A5075706781 @default.
- W2023514819 creator A5076668920 @default.
- W2023514819 creator A5078736303 @default.
- W2023514819 date "2013-04-01" @default.
- W2023514819 modified "2023-09-24" @default.
- W2023514819 title "Determination of nicousamide in human plasma by liquid chromatography–tandem mass spectrometry" @default.
- W2023514819 cites W1991652641 @default.
- W2023514819 cites W2043867801 @default.
- W2023514819 cites W2073075566 @default.
- W2023514819 cites W2093769633 @default.
- W2023514819 cites W2138774341 @default.
- W2023514819 cites W2273875352 @default.
- W2023514819 cites W2098460778 @default.
- W2023514819 doi "https://doi.org/10.1016/j.jpba.2013.01.025" @default.
- W2023514819 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23416370" @default.
- W2023514819 hasPublicationYear "2013" @default.
- W2023514819 type Work @default.
- W2023514819 sameAs 2023514819 @default.
- W2023514819 citedByCount "0" @default.
- W2023514819 crossrefType "journal-article" @default.
- W2023514819 hasAuthorship W2023514819A5002891743 @default.
- W2023514819 hasAuthorship W2023514819A5024827414 @default.
- W2023514819 hasAuthorship W2023514819A5064307000 @default.
- W2023514819 hasAuthorship W2023514819A5075706781 @default.
- W2023514819 hasAuthorship W2023514819A5076668920 @default.
- W2023514819 hasAuthorship W2023514819A5078736303 @default.
- W2023514819 hasConcept C113196181 @default.
- W2023514819 hasConcept C119128265 @default.
- W2023514819 hasConcept C162356407 @default.
- W2023514819 hasConcept C179998833 @default.
- W2023514819 hasConcept C185592680 @default.
- W2023514819 hasConcept C31827203 @default.
- W2023514819 hasConcept C43617362 @default.
- W2023514819 hasConcept C64489805 @default.
- W2023514819 hasConcept C71043704 @default.
- W2023514819 hasConceptScore W2023514819C113196181 @default.
- W2023514819 hasConceptScore W2023514819C119128265 @default.
- W2023514819 hasConceptScore W2023514819C162356407 @default.
- W2023514819 hasConceptScore W2023514819C179998833 @default.
- W2023514819 hasConceptScore W2023514819C185592680 @default.
- W2023514819 hasConceptScore W2023514819C31827203 @default.
- W2023514819 hasConceptScore W2023514819C43617362 @default.
- W2023514819 hasConceptScore W2023514819C64489805 @default.
- W2023514819 hasConceptScore W2023514819C71043704 @default.
- W2023514819 hasLocation W20235148191 @default.
- W2023514819 hasLocation W20235148192 @default.
- W2023514819 hasOpenAccess W2023514819 @default.
- W2023514819 hasPrimaryLocation W20235148191 @default.
- W2023514819 hasRelatedWork W1981763116 @default.
- W2023514819 hasRelatedWork W1994399095 @default.
- W2023514819 hasRelatedWork W2020202396 @default.
- W2023514819 hasRelatedWork W2024409696 @default.
- W2023514819 hasRelatedWork W2035757008 @default.
- W2023514819 hasRelatedWork W2036118159 @default.
- W2023514819 hasRelatedWork W2050060039 @default.
- W2023514819 hasRelatedWork W2060279488 @default.
- W2023514819 hasRelatedWork W2069045468 @default.
- W2023514819 hasRelatedWork W2075095937 @default.
- W2023514819 hasRelatedWork W2088031146 @default.
- W2023514819 hasRelatedWork W2140250851 @default.
- W2023514819 hasRelatedWork W2157120814 @default.
- W2023514819 hasRelatedWork W2161896865 @default.
- W2023514819 hasRelatedWork W2167242391 @default.
- W2023514819 hasRelatedWork W2229858648 @default.
- W2023514819 hasRelatedWork W2331436727 @default.
- W2023514819 hasRelatedWork W2355687126 @default.
- W2023514819 hasRelatedWork W2473340444 @default.
- W2023514819 hasRelatedWork W2947206133 @default.
- W2023514819 hasVolume "77" @default.
- W2023514819 isParatext "false" @default.
- W2023514819 isRetracted "false" @default.
- W2023514819 magId "2023514819" @default.
- W2023514819 workType "article" @default.