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- W2023521338 abstract "Three-component reactions of 4-cyanopyridine or ethyl isonicotinate with electron-deficient alkynes and isatins in dimethoxyethane at room temperature afforded spiro[3H-indole-3,2′-[2H,9aH-pyrido[2,1-b][1,3]oxazine] derivatives. Alternately, the similar three-component reaction at elevated temperature resulted in polycyclic dispirooxindole derivatives. The reaction mechanism is believed to involve sequential generation and cycloaddition of Huisgen's 1,4-dipole, and Diels–Alder cyclodimerization reaction. The similar three-component reactions containing acenaphthenequinone and phenanthrenequinone also afforded corresponding polyheterocyclic derivatives." @default.
- W2023521338 created "2016-06-24" @default.
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- W2023521338 date "2014-09-01" @default.
- W2023521338 modified "2023-09-28" @default.
- W2023521338 title "Efficient synthesis of polycyclic dispirooxindoles via domino Diels–Alder cyclodimerization reaction" @default.
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- W2023521338 doi "https://doi.org/10.1016/j.tet.2014.06.097" @default.
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