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- W2023521644 abstract "Antiphospholipid syndrome is a systemic autoimmune disease with heterogeneous clinical manifestations and different patterns of expression. Thus, the outcome can be unpredictable with different degrees of severity. It is known to be a potentially devastating disease that occurs among young individuals with increased morbidity, organ damage, and mortality during the course of the disease. Patients with triple positivity (lupus anticoagulant, anticardiolipin, and anti-β2-glycoprotein I antibodies) have the worst prognosis due to increased recurrence of thrombotic and obstetric complications. The organ failure is mainly secondary to recurrent thrombosis, especially arterial events. The neurologic involvement is associated with the worst outcome due to negative influence on the quality of life. Nevertheless, there is scarce information about prognosis, risk factors, and organ damage predictors and further studies will be necessary." @default.
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- W2023521644 date "2000-09-01" @default.
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- W2023521644 title "Long-term Prognosis of Antiphospholipid Syndrome in Patients with Systemic Lupus Erythematosus" @default.
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- W2023521644 doi "https://doi.org/10.1006/jaut.2000.0402" @default.
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