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- W2023530170 abstract "Two iron regulatory proteins (IRP1 and IRP2) regulate translation and/or stability of mRNAs encoding proteins required for iron storage, acquisition and utilization. Rather than IRP2 directly sensing iron concentrations, iron has been shown to regulate the level of the SKP1-CUL1-FBXL5 E3 ubiquitin ligase protein complex, which is responsible for IRP2 degradation." @default.
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- W2023530170 date "2009-12-01" @default.
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- W2023530170 title "On the mechanism of iron sensing by IRP2: new players, new paradigms" @default.
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- W2023530170 doi "https://doi.org/10.1038/nchembio.261" @default.
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