FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023531744> ?p ?o ?g. }

• W2023531744 endingPage "8" @default.
• W2023531744 startingPage "1" @default.
• W2023531744 abstract "The aim of the present work was to clarify the role of calcium influx through L-type calcium channels in the rewarding and analgesic effects of morphine. Therefore the effects of Bay K-8644 and nimodipine, dihydropyridine calcium agonist and antagonist, respectively, on the analgesic and rewarding effects of morphine in mice were studied. Morphine-induced analgesia was measured with the aid of writhing test, hot plate test and tail clip test. The rewarding properties of morphine were studied using i.v. self-administration in drug-naive mice. Bay K-8644 potentiated morphine-induced analgesia in all the tests. The influence of nimodipine on morphine analgesia was more complicated and depended on the dose of morphine and test used. In self-administration experiments morphine exhibited the bell-shaped concentration-response curve. Bay K-8644 produced a shift of the curve to the left, while nimodipine had the opposite action indicating, respectively, facilitating and inhibitory influence on morphine rewarding effect. It is concluded that nimodipine exhibits partial antagonistic properties towards the rewarding action of morphine and slightly potentiates morphine-induced analgesia while Bay K-8644 increases either the rewarding or the analgesic effects of morphine." @default.
• W2023531744 created "2016-06-24" @default.
• W2023531744 creator A5005988182 @default.
• W2023531744 creator A5028959450 @default.
• W2023531744 creator A5057190193 @default.
• W2023531744 date "1994-07-01" @default.
• W2023531744 modified "2023-09-27" @default.
• W2023531744 title "Analgesic and reinforcing effects of morphine in mice. Influence of Bay K-8644 and nimodipine" @default.
• W2023531744 cites W1582263310 @default.
• W2023531744 cites W1853262789 @default.
• W2023531744 cites W1964295968 @default.
• W2023531744 cites W1972001212 @default.
• W2023531744 cites W1975587096 @default.
• W2023531744 cites W1983453735 @default.
• W2023531744 cites W1984094514 @default.
• W2023531744 cites W1993527712 @default.
• W2023531744 cites W1994615753 @default.
• W2023531744 cites W2000781318 @default.
• W2023531744 cites W2007529978 @default.
• W2023531744 cites W2009412632 @default.
• W2023531744 cites W2014071555 @default.
• W2023531744 cites W2026284849 @default.
• W2023531744 cites W2034624827 @default.
• W2023531744 cites W2042605833 @default.
• W2023531744 cites W2043404918 @default.
• W2023531744 cites W2047458497 @default.
• W2023531744 cites W2053559739 @default.
• W2023531744 cites W2056029104 @default.
• W2023531744 cites W2056660986 @default.
• W2023531744 cites W2060533392 @default.
• W2023531744 cites W2070664473 @default.
• W2023531744 cites W2071467710 @default.
• W2023531744 cites W2072115108 @default.
• W2023531744 cites W2072241600 @default.
• W2023531744 cites W2080165573 @default.
• W2023531744 cites W2081726150 @default.
• W2023531744 cites W2098520750 @default.
• W2023531744 cites W2110378189 @default.
• W2023531744 cites W2130644900 @default.
• W2023531744 cites W2131572345 @default.
• W2023531744 cites W2136656184 @default.
• W2023531744 cites W2314142643 @default.
• W2023531744 doi "https://doi.org/10.1016/0006-8993(94)90310-7" @default.
• W2023531744 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7525018" @default.
• W2023531744 hasPublicationYear "1994" @default.
• W2023531744 type Work @default.
• W2023531744 sameAs 2023531744 @default.
• W2023531744 citedByCount "23" @default.
• W2023531744 countsByYear W20235317442012 @default.
• W2023531744 countsByYear W20235317442013 @default.
• W2023531744 countsByYear W20235317442018 @default.
• W2023531744 countsByYear W20235317442021 @default.
• W2023531744 crossrefType "journal-article" @default.
• W2023531744 hasAuthorship W2023531744A5005988182 @default.
• W2023531744 hasAuthorship W2023531744A5028959450 @default.
• W2023531744 hasAuthorship W2023531744A5057190193 @default.
• W2023531744 hasConcept C126322002 @default.
• W2023531744 hasConcept C170493617 @default.
• W2023531744 hasConcept C185592680 @default.
• W2023531744 hasConcept C2776885963 @default.
• W2023531744 hasConcept C2777294900 @default.
• W2023531744 hasConcept C2777389121 @default.
• W2023531744 hasConcept C2778938600 @default.
• W2023531744 hasConcept C2780820201 @default.
• W2023531744 hasConcept C2781212610 @default.
• W2023531744 hasConcept C42219234 @default.
• W2023531744 hasConcept C519063684 @default.
• W2023531744 hasConcept C71924100 @default.
• W2023531744 hasConcept C98274493 @default.
• W2023531744 hasConceptScore W2023531744C126322002 @default.
• W2023531744 hasConceptScore W2023531744C170493617 @default.
• W2023531744 hasConceptScore W2023531744C185592680 @default.
• W2023531744 hasConceptScore W2023531744C2776885963 @default.
• W2023531744 hasConceptScore W2023531744C2777294900 @default.
• W2023531744 hasConceptScore W2023531744C2777389121 @default.
• W2023531744 hasConceptScore W2023531744C2778938600 @default.
• W2023531744 hasConceptScore W2023531744C2780820201 @default.
• W2023531744 hasConceptScore W2023531744C2781212610 @default.
• W2023531744 hasConceptScore W2023531744C42219234 @default.
• W2023531744 hasConceptScore W2023531744C519063684 @default.
• W2023531744 hasConceptScore W2023531744C71924100 @default.
• W2023531744 hasConceptScore W2023531744C98274493 @default.
• W2023531744 hasIssue "1" @default.
• W2023531744 hasLocation W20235317441 @default.
• W2023531744 hasLocation W20235317442 @default.
• W2023531744 hasOpenAccess W2023531744 @default.
• W2023531744 hasPrimaryLocation W20235317441 @default.
• W2023531744 hasRelatedWork W1565370780 @default.
• W2023531744 hasRelatedWork W1996681578 @default.
• W2023531744 hasRelatedWork W2015591170 @default.
• W2023531744 hasRelatedWork W2019157459 @default.
• W2023531744 hasRelatedWork W2043197240 @default.
• W2023531744 hasRelatedWork W2084650733 @default.
• W2023531744 hasRelatedWork W2140502563 @default.
• W2023531744 hasRelatedWork W4206871862 @default.
• W2023531744 hasRelatedWork W4287435042 @default.
• W2023531744 hasRelatedWork W94940270 @default.
• W2023531744 hasVolume "652" @default.

• next