FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023540718> ?p ?o ?g. }

• W2023540718 endingPage "686" @default.
• W2023540718 startingPage "682" @default.
• W2023540718 abstract "We studied the effects of the endogenous cannabinoid ligand anandamide on blood pressure, single unit activity of barosensitive neurons in the rostral ventrolateral medulla, and postganglionic splanchnic sympathetic nerve discharge in urethane-anesthetized rats. In rats with an intact baroreflex, an intravenous bolus of 4 mg/kg anandamide caused a triphasic blood pressure response: transient hypotension, followed by a brief pressor and more prolonged depressor phase. Anandamide evoked a “primary” increase in neuronal firing coincident with its pressor effect and a “secondary,” baroreflex-mediated rise coincident with its depressor effect at both sites. Pretreatment of rats with phentolamine or trimethaphan did not inhibit either the pressor response or the primary increase in splanchnic nerve discharge elicited by anandamide. In barodenervated rats, electrical stimulation of the rostral ventrolateral medulla increased blood pressure and splanchnic nerve discharge. Anandamide treatment blunted the rise in blood pressure without affecting the increase in splanchnic nerve discharge. Anandamide did not affect the rise in blood pressure in response to an intravenous bolus dose of phenylephrine. The results indicate that (1) the brief pressor response to anandamide is not sympathetically mediated, and (2) the prolonged hypotensive response to anandamide is not initiated in the central nervous system, in ganglia, or at postsynaptic adrenergic receptors but is due to a presynaptic action that inhibits norepinephrine release from sympathetic nerve terminals in the heart and vasculature." @default.
• W2023540718 created "2016-06-24" @default.
• W2023540718 creator A5026132845 @default.
• W2023540718 creator A5052303639 @default.
• W2023540718 creator A5081637927 @default.
• W2023540718 creator A5086403131 @default.
• W2023540718 creator A5090361193 @default.
• W2023540718 date "1996-10-01" @default.
• W2023540718 modified "2023-09-25" @default.
• W2023540718 title "Mechanism of the Hypotensive Action of Anandamide in Anesthetized Rats" @default.
• W2023540718 cites W1989073099 @default.
• W2023540718 cites W2002445186 @default.
• W2023540718 cites W2012515198 @default.
• W2023540718 cites W2043303731 @default.
• W2023540718 cites W2056188558 @default.
• W2023540718 cites W2059977407 @default.
• W2023540718 cites W2066264017 @default.
• W2023540718 cites W2072721884 @default.
• W2023540718 cites W2075894678 @default.
• W2023540718 cites W2077413830 @default.
• W2023540718 cites W2081525307 @default.
• W2023540718 cites W4318900669 @default.
• W2023540718 doi "https://doi.org/10.1161/01.hyp.28.4.682" @default.
• W2023540718 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8843898" @default.
• W2023540718 hasPublicationYear "1996" @default.
• W2023540718 type Work @default.
• W2023540718 sameAs 2023540718 @default.
• W2023540718 citedByCount "143" @default.
• W2023540718 countsByYear W20235407182012 @default.
• W2023540718 countsByYear W20235407182013 @default.
• W2023540718 countsByYear W20235407182014 @default.
• W2023540718 countsByYear W20235407182015 @default.
• W2023540718 countsByYear W20235407182016 @default.
• W2023540718 countsByYear W20235407182017 @default.
• W2023540718 countsByYear W20235407182018 @default.
• W2023540718 countsByYear W20235407182019 @default.
• W2023540718 countsByYear W20235407182020 @default.
• W2023540718 countsByYear W20235407182021 @default.
• W2023540718 countsByYear W20235407182022 @default.
• W2023540718 countsByYear W20235407182023 @default.
• W2023540718 crossrefType "journal-article" @default.
• W2023540718 hasAuthorship W2023540718A5026132845 @default.
• W2023540718 hasAuthorship W2023540718A5052303639 @default.
• W2023540718 hasAuthorship W2023540718A5081637927 @default.
• W2023540718 hasAuthorship W2023540718A5086403131 @default.
• W2023540718 hasAuthorship W2023540718A5090361193 @default.
• W2023540718 hasConcept C126322002 @default.
• W2023540718 hasConcept C134018914 @default.
• W2023540718 hasConcept C148001335 @default.
• W2023540718 hasConcept C170493617 @default.
• W2023540718 hasConcept C178853913 @default.
• W2023540718 hasConcept C191237925 @default.
• W2023540718 hasConcept C24998067 @default.
• W2023540718 hasConcept C2775849017 @default.
• W2023540718 hasConcept C2776533406 @default.
• W2023540718 hasConcept C2777952589 @default.
• W2023540718 hasConcept C2777953023 @default.
• W2023540718 hasConcept C2778938600 @default.
• W2023540718 hasConcept C2779783865 @default.
• W2023540718 hasConcept C2780253649 @default.
• W2023540718 hasConcept C2780661788 @default.
• W2023540718 hasConcept C33114225 @default.
• W2023540718 hasConcept C42219234 @default.
• W2023540718 hasConcept C71924100 @default.
• W2023540718 hasConcept C79752029 @default.
• W2023540718 hasConcept C84393581 @default.
• W2023540718 hasConceptScore W2023540718C126322002 @default.
• W2023540718 hasConceptScore W2023540718C134018914 @default.
• W2023540718 hasConceptScore W2023540718C148001335 @default.
• W2023540718 hasConceptScore W2023540718C170493617 @default.
• W2023540718 hasConceptScore W2023540718C178853913 @default.
• W2023540718 hasConceptScore W2023540718C191237925 @default.
• W2023540718 hasConceptScore W2023540718C24998067 @default.
• W2023540718 hasConceptScore W2023540718C2775849017 @default.
• W2023540718 hasConceptScore W2023540718C2776533406 @default.
• W2023540718 hasConceptScore W2023540718C2777952589 @default.
• W2023540718 hasConceptScore W2023540718C2777953023 @default.
• W2023540718 hasConceptScore W2023540718C2778938600 @default.
• W2023540718 hasConceptScore W2023540718C2779783865 @default.
• W2023540718 hasConceptScore W2023540718C2780253649 @default.
• W2023540718 hasConceptScore W2023540718C2780661788 @default.
• W2023540718 hasConceptScore W2023540718C33114225 @default.
• W2023540718 hasConceptScore W2023540718C42219234 @default.
• W2023540718 hasConceptScore W2023540718C71924100 @default.
• W2023540718 hasConceptScore W2023540718C79752029 @default.
• W2023540718 hasConceptScore W2023540718C84393581 @default.
• W2023540718 hasIssue "4" @default.
• W2023540718 hasLocation W20235407181 @default.
• W2023540718 hasLocation W20235407182 @default.
• W2023540718 hasOpenAccess W2023540718 @default.
• W2023540718 hasPrimaryLocation W20235407181 @default.
• W2023540718 hasRelatedWork W2023540718 @default.
• W2023540718 hasRelatedWork W2046401998 @default.
• W2023540718 hasRelatedWork W2078656441 @default.
• W2023540718 hasRelatedWork W2093020482 @default.
• W2023540718 hasRelatedWork W2111230444 @default.
• W2023540718 hasRelatedWork W2140722868 @default.
• W2023540718 hasRelatedWork W2314968924 @default.

• next