Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023540863> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2023540863 endingPage "116" @default.
- W2023540863 startingPage "113" @default.
- W2023540863 abstract "K+ channels are essential for a variety of cellular functions in both excitable and nonexcitable cells, and K+ channel gene alteration has been recently described in cardiac and neurological disorders. To explore further the relations between hereditary human diseases and K+ channels, we isolated from a human cosmid library the gene encoding the inwardly rectifying K+ channel alpha-subunit Kir 2.2 (KCNJ12). PCR analysis performed on this clone indicates that the entire open reading frame is contained in one unique exon. A polymorphic (CA)16 sequence was localized 2.2 kb upstream of the ATG start codon. Fluorescence in situ hybridization on human metaphases assigns the gene to band 17p11.1. The implication of a deletion of the Kir 2.2 gene in the Smith-Magenis syndrome, which is also localized at 17p11, is unlikely since a Kir 2.2-linked microsatellite sequence could be amplified from the DNA of a Smith-Magenis syndrome affected patient bearing a 17p interstitial deletion." @default.
- W2023540863 created "2016-06-24" @default.
- W2023540863 creator A5020004980 @default.
- W2023540863 creator A5020901177 @default.
- W2023540863 creator A5027449306 @default.
- W2023540863 creator A5043746560 @default.
- W2023540863 creator A5068045779 @default.
- W2023540863 creator A5073516930 @default.
- W2023540863 creator A5087907084 @default.
- W2023540863 date "1997-01-01" @default.
- W2023540863 modified "2023-10-17" @default.
- W2023540863 title "The Human Inward Rectifying K+Channel Kir 2.2 (KCNJ12) Gene: Gene Structure, Assignment to Chromosome 17p11.1, and Identification of a Simple Tandem Repeat Polymorphism" @default.
- W2023540863 doi "https://doi.org/10.1006/geno.1996.4450" @default.
- W2023540863 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9027495" @default.
- W2023540863 hasPublicationYear "1997" @default.
- W2023540863 type Work @default.
- W2023540863 sameAs 2023540863 @default.
- W2023540863 citedByCount "19" @default.
- W2023540863 countsByYear W20235408632012 @default.
- W2023540863 countsByYear W20235408632014 @default.
- W2023540863 countsByYear W20235408632016 @default.
- W2023540863 countsByYear W20235408632017 @default.
- W2023540863 countsByYear W20235408632018 @default.
- W2023540863 countsByYear W20235408632021 @default.
- W2023540863 countsByYear W20235408632023 @default.
- W2023540863 crossrefType "journal-article" @default.
- W2023540863 hasAuthorship W2023540863A5020004980 @default.
- W2023540863 hasAuthorship W2023540863A5020901177 @default.
- W2023540863 hasAuthorship W2023540863A5027449306 @default.
- W2023540863 hasAuthorship W2023540863A5043746560 @default.
- W2023540863 hasAuthorship W2023540863A5068045779 @default.
- W2023540863 hasAuthorship W2023540863A5073516930 @default.
- W2023540863 hasAuthorship W2023540863A5087907084 @default.
- W2023540863 hasConcept C104317684 @default.
- W2023540863 hasConcept C122735190 @default.
- W2023540863 hasConcept C153911025 @default.
- W2023540863 hasConcept C30481170 @default.
- W2023540863 hasConcept C35101798 @default.
- W2023540863 hasConcept C36823959 @default.
- W2023540863 hasConcept C54355233 @default.
- W2023540863 hasConcept C86803240 @default.
- W2023540863 hasConceptScore W2023540863C104317684 @default.
- W2023540863 hasConceptScore W2023540863C122735190 @default.
- W2023540863 hasConceptScore W2023540863C153911025 @default.
- W2023540863 hasConceptScore W2023540863C30481170 @default.
- W2023540863 hasConceptScore W2023540863C35101798 @default.
- W2023540863 hasConceptScore W2023540863C36823959 @default.
- W2023540863 hasConceptScore W2023540863C54355233 @default.
- W2023540863 hasConceptScore W2023540863C86803240 @default.
- W2023540863 hasIssue "1" @default.
- W2023540863 hasLocation W20235408631 @default.
- W2023540863 hasLocation W20235408632 @default.
- W2023540863 hasOpenAccess W2023540863 @default.
- W2023540863 hasPrimaryLocation W20235408631 @default.
- W2023540863 hasRelatedWork W1866648957 @default.
- W2023540863 hasRelatedWork W1993811467 @default.
- W2023540863 hasRelatedWork W2008510086 @default.
- W2023540863 hasRelatedWork W2025851750 @default.
- W2023540863 hasRelatedWork W2031436818 @default.
- W2023540863 hasRelatedWork W2039352533 @default.
- W2023540863 hasRelatedWork W2042308282 @default.
- W2023540863 hasRelatedWork W2068616163 @default.
- W2023540863 hasRelatedWork W2091106956 @default.
- W2023540863 hasRelatedWork W2168467210 @default.
- W2023540863 hasVolume "39" @default.
- W2023540863 isParatext "false" @default.
- W2023540863 isRetracted "false" @default.
- W2023540863 magId "2023540863" @default.
- W2023540863 workType "article" @default.