Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023542962> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2023542962 endingPage "1099" @default.
- W2023542962 startingPage "1093" @default.
- W2023542962 abstract "It is standard practice to use multiple outcome measures in rheumatoid arthritis (RA) clinical trials. Because of this, multiple testing is usually done, and there is confusion in the interpretation of the results. It is not clear which measures are the most sensitive to detecting improvement and which provide independent information. To address these questions, we conducted an analysis of pooled raw data from 3 placebo-controlled RA trials: one of methotrexate, another of oral and injectable gold, and the third of low-dose and high-dose D-penicillamine. The results show that the joint tenderness count, erythrocyte sedimentation rate, grip strength, and physician assessment of disease activity perform best in RA clinical trials and cover the domain of change measured by traditional outcome measures. Other clinical measures may provide little additional useful information for a standard therapeutic trial of up to 6 months duration, and some measures, such as the proximal interphalangeal joint circumference, hemoglobin level, and 50-foot walking time, can be eliminated from such trials." @default.
- W2023542962 created "2016-06-24" @default.
- W2023542962 creator A5013708093 @default.
- W2023542962 creator A5069725714 @default.
- W2023542962 creator A5077883927 @default.
- W2023542962 creator A5084884266 @default.
- W2023542962 date "1989-09-01" @default.
- W2023542962 modified "2023-10-14" @default.
- W2023542962 title "Which traditional measures should be used in rheumatoid arthritis clinical trials?" @default.
- W2023542962 cites W2024691000 @default.
- W2023542962 cites W2054888624 @default.
- W2023542962 cites W2058513103 @default.
- W2023542962 cites W2070121713 @default.
- W2023542962 cites W2071866500 @default.
- W2023542962 cites W2093319342 @default.
- W2023542962 cites W2103163020 @default.
- W2023542962 cites W2111639672 @default.
- W2023542962 cites W2112836912 @default.
- W2023542962 cites W2157825442 @default.
- W2023542962 cites W2331320446 @default.
- W2023542962 cites W2443468429 @default.
- W2023542962 doi "https://doi.org/10.1002/anr.1780320907" @default.
- W2023542962 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2505779" @default.
- W2023542962 hasPublicationYear "1989" @default.
- W2023542962 type Work @default.
- W2023542962 sameAs 2023542962 @default.
- W2023542962 citedByCount "127" @default.
- W2023542962 countsByYear W20235429622012 @default.
- W2023542962 countsByYear W20235429622014 @default.
- W2023542962 countsByYear W20235429622016 @default.
- W2023542962 countsByYear W20235429622017 @default.
- W2023542962 countsByYear W20235429622018 @default.
- W2023542962 countsByYear W20235429622021 @default.
- W2023542962 crossrefType "journal-article" @default.
- W2023542962 hasAuthorship W2023542962A5013708093 @default.
- W2023542962 hasAuthorship W2023542962A5069725714 @default.
- W2023542962 hasAuthorship W2023542962A5077883927 @default.
- W2023542962 hasAuthorship W2023542962A5084884266 @default.
- W2023542962 hasBestOaLocation W20235429621 @default.
- W2023542962 hasConcept C126322002 @default.
- W2023542962 hasConcept C142724271 @default.
- W2023542962 hasConcept C1862650 @default.
- W2023542962 hasConcept C204787440 @default.
- W2023542962 hasConcept C27081682 @default.
- W2023542962 hasConcept C2777433710 @default.
- W2023542962 hasConcept C2777575956 @default.
- W2023542962 hasConcept C2778143017 @default.
- W2023542962 hasConcept C40993552 @default.
- W2023542962 hasConcept C535046627 @default.
- W2023542962 hasConcept C71924100 @default.
- W2023542962 hasConceptScore W2023542962C126322002 @default.
- W2023542962 hasConceptScore W2023542962C142724271 @default.
- W2023542962 hasConceptScore W2023542962C1862650 @default.
- W2023542962 hasConceptScore W2023542962C204787440 @default.
- W2023542962 hasConceptScore W2023542962C27081682 @default.
- W2023542962 hasConceptScore W2023542962C2777433710 @default.
- W2023542962 hasConceptScore W2023542962C2777575956 @default.
- W2023542962 hasConceptScore W2023542962C2778143017 @default.
- W2023542962 hasConceptScore W2023542962C40993552 @default.
- W2023542962 hasConceptScore W2023542962C535046627 @default.
- W2023542962 hasConceptScore W2023542962C71924100 @default.
- W2023542962 hasIssue "9" @default.
- W2023542962 hasLocation W20235429621 @default.
- W2023542962 hasLocation W20235429622 @default.
- W2023542962 hasOpenAccess W2023542962 @default.
- W2023542962 hasPrimaryLocation W20235429621 @default.
- W2023542962 hasRelatedWork W1966743572 @default.
- W2023542962 hasRelatedWork W2007650860 @default.
- W2023542962 hasRelatedWork W2082533755 @default.
- W2023542962 hasRelatedWork W2302840914 @default.
- W2023542962 hasRelatedWork W2339707069 @default.
- W2023542962 hasRelatedWork W2409267851 @default.
- W2023542962 hasRelatedWork W2416843927 @default.
- W2023542962 hasRelatedWork W2418176634 @default.
- W2023542962 hasRelatedWork W2579980627 @default.
- W2023542962 hasRelatedWork W2972050921 @default.
- W2023542962 hasVolume "32" @default.
- W2023542962 isParatext "false" @default.
- W2023542962 isRetracted "false" @default.
- W2023542962 magId "2023542962" @default.
- W2023542962 workType "article" @default.