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• W2023543886 abstract "Parasite loads were quantified in repeated skin biopsies from lesions of 2 patients with Old-World cutaneous leishmaniasis (CL) caused by Leishmania major and L. infantum during and after treatment with miltefosine. Miltefosine induced a rapid therapeutic effect on both infections with an initial decline of parasites of ∼1 log/week for the L. major infection. These observations illustrate the usability of quantifying parasite loads in skin lesions as a pharmacodynamic measure and quantitative descriptor of drug effect for CL supporting clinical assessment." @default.
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• W2023543886 date "2011-12-13" @default.
• W2023543886 modified "2023-10-16" @default.
• W2023543886 title "Dynamics of Parasite Clearance in Cutaneous Leishmaniasis Patients Treated with Miltefosine" @default.
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• W2023543886 doi "https://doi.org/10.1371/journal.pntd.0001436" @default.
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