Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023544056> ?p ?o ?g. }
- W2023544056 endingPage "1748" @default.
- W2023544056 startingPage "1739" @default.
- W2023544056 abstract "Background Left ventricular (LV) hypertrophy, as measured by M-mode echocardiography, is an independent predictor of mortality and/or morbidity from coronary heart disease (CHD). LV global and segmental systolic dysfunction also have been associated with myocardial ischemia and cardiovascular morbidity and mortality. Echocardiographic data, especially two-dimensional, have not been available previously from multicenter-based studies of the elderly. This report describes the distribution and relation at baseline of echocardiographic LV mass and global and segmental LV wall motion to age, sex, and clinical disease category in the Cardiovascular Health Study (CHS), a cohort of 5201 men and women (4850 white) 65 years of age and older. Methods and Results M-mode LV mass adjusted for body weight increased modestly with age ( P <.0001), increasing less than one gram per year increase in age for both men and women. After adjustment for weight, LV mass was significantly greater in men than in women and in participants with clinical CHD compared with participants with neither clinical heart disease nor hypertension (both P <.001). Across all CHS age subgroups, the difference in weight-adjusted LV mass by sex was greater in magnitude than the difference related to clinical CHD. M-mode measurements of LV mass could not be made in 34% of CHS participants, and this was highly related to age (29% in the 65 to 69 year versus 50% in the 85+ year age group, P <.001) and other risk factors. In participants with clinical CHD and with neither clinical heart disease nor hypertension, LV ejection fraction and segmental wall motion abnormalities were more prevalent in men than women (all P <.001). Of interest, 0.5% of men and 0.4% of women with neither clinical heart disease nor hypertension had LV segmental wall motion abnormalities, suggesting silent disease, compared with 26% of men and 10% of women in the clinical CHD group ( P <.0001). Multivariate analyses revealed male sex and presence of clinical CHD (both P <.001) to be independent predictors of LV akinesis or dyskinesis. Conclusions Significant baseline relations were detected between differences in sex, prevalent disease status, and echocardiographic measurements of LV mass and systolic function in the CHS cohort. Age was weakly associated with LV mass measurements and LV ejection fraction abnormalities. These relations should be considered in evaluating the preclinical and clinical effects of CHD risk factors in the elderly." @default.
- W2023544056 created "2016-06-24" @default.
- W2023544056 creator A5010410773 @default.
- W2023544056 creator A5017386283 @default.
- W2023544056 creator A5017572190 @default.
- W2023544056 creator A5050967253 @default.
- W2023544056 creator A5051575786 @default.
- W2023544056 creator A5054880512 @default.
- W2023544056 creator A5065525518 @default.
- W2023544056 creator A5078278017 @default.
- W2023544056 creator A5079554237 @default.
- W2023544056 creator A5089568993 @default.
- W2023544056 date "1995-03-15" @default.
- W2023544056 modified "2023-10-16" @default.
- W2023544056 title "Sex, Age, and Disease Affect Echocardiographic Left Ventricular Mass and Systolic Function in the Free-Living Elderly" @default.
- W2023544056 cites W1859070379 @default.
- W2023544056 cites W1973820984 @default.
- W2023544056 cites W1975925766 @default.
- W2023544056 cites W1982660098 @default.
- W2023544056 cites W1992141724 @default.
- W2023544056 cites W1996946370 @default.
- W2023544056 cites W2004216982 @default.
- W2023544056 cites W2021541864 @default.
- W2023544056 cites W2030706068 @default.
- W2023544056 cites W2032556546 @default.
- W2023544056 cites W2034177003 @default.
- W2023544056 cites W2042293234 @default.
- W2023544056 cites W2048720788 @default.
- W2023544056 cites W2051094006 @default.
- W2023544056 cites W2082197759 @default.
- W2023544056 cites W2161197885 @default.
- W2023544056 cites W2334499091 @default.
- W2023544056 doi "https://doi.org/10.1161/01.cir.91.6.1739" @default.
- W2023544056 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7882482" @default.
- W2023544056 hasPublicationYear "1995" @default.
- W2023544056 type Work @default.
- W2023544056 sameAs 2023544056 @default.
- W2023544056 citedByCount "221" @default.
- W2023544056 countsByYear W20235440562012 @default.
- W2023544056 countsByYear W20235440562013 @default.
- W2023544056 countsByYear W20235440562014 @default.
- W2023544056 countsByYear W20235440562015 @default.
- W2023544056 countsByYear W20235440562016 @default.
- W2023544056 countsByYear W20235440562017 @default.
- W2023544056 countsByYear W20235440562018 @default.
- W2023544056 countsByYear W20235440562019 @default.
- W2023544056 countsByYear W20235440562020 @default.
- W2023544056 countsByYear W20235440562021 @default.
- W2023544056 countsByYear W20235440562022 @default.
- W2023544056 countsByYear W20235440562023 @default.
- W2023544056 crossrefType "journal-article" @default.
- W2023544056 hasAuthorship W2023544056A5010410773 @default.
- W2023544056 hasAuthorship W2023544056A5017386283 @default.
- W2023544056 hasAuthorship W2023544056A5017572190 @default.
- W2023544056 hasAuthorship W2023544056A5050967253 @default.
- W2023544056 hasAuthorship W2023544056A5051575786 @default.
- W2023544056 hasAuthorship W2023544056A5054880512 @default.
- W2023544056 hasAuthorship W2023544056A5065525518 @default.
- W2023544056 hasAuthorship W2023544056A5078278017 @default.
- W2023544056 hasAuthorship W2023544056A5079554237 @default.
- W2023544056 hasAuthorship W2023544056A5089568993 @default.
- W2023544056 hasConcept C126322002 @default.
- W2023544056 hasConcept C164705383 @default.
- W2023544056 hasConcept C2776002628 @default.
- W2023544056 hasConcept C2778198053 @default.
- W2023544056 hasConcept C2778213512 @default.
- W2023544056 hasConcept C2780221984 @default.
- W2023544056 hasConcept C71924100 @default.
- W2023544056 hasConcept C72563966 @default.
- W2023544056 hasConcept C84393581 @default.
- W2023544056 hasConceptScore W2023544056C126322002 @default.
- W2023544056 hasConceptScore W2023544056C164705383 @default.
- W2023544056 hasConceptScore W2023544056C2776002628 @default.
- W2023544056 hasConceptScore W2023544056C2778198053 @default.
- W2023544056 hasConceptScore W2023544056C2778213512 @default.
- W2023544056 hasConceptScore W2023544056C2780221984 @default.
- W2023544056 hasConceptScore W2023544056C71924100 @default.
- W2023544056 hasConceptScore W2023544056C72563966 @default.
- W2023544056 hasConceptScore W2023544056C84393581 @default.
- W2023544056 hasIssue "6" @default.
- W2023544056 hasLocation W20235440561 @default.
- W2023544056 hasLocation W20235440562 @default.
- W2023544056 hasOpenAccess W2023544056 @default.
- W2023544056 hasPrimaryLocation W20235440561 @default.
- W2023544056 hasRelatedWork W1486551637 @default.
- W2023544056 hasRelatedWork W1553859198 @default.
- W2023544056 hasRelatedWork W1992046973 @default.
- W2023544056 hasRelatedWork W2099628268 @default.
- W2023544056 hasRelatedWork W2164703220 @default.
- W2023544056 hasRelatedWork W2383994333 @default.
- W2023544056 hasRelatedWork W44894489 @default.
- W2023544056 hasRelatedWork W55173076 @default.
- W2023544056 hasRelatedWork W588655279 @default.
- W2023544056 hasRelatedWork W642714463 @default.
- W2023544056 hasVolume "91" @default.
- W2023544056 isParatext "false" @default.
- W2023544056 isRetracted "false" @default.
- W2023544056 magId "2023544056" @default.