FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023554954> ?p ?o ?g. }

• W2023554954 endingPage "1023" @default.
• W2023554954 startingPage "1023" @default.
• W2023554954 abstract "<b>1097</b> <h3><b>Background:</b></h3> Functional imaging with 18F-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography(PET/CT) is increasingly used for diagnosis and staging and restaging of breast cancer (BC) patients. <h3><b>Purpose:</b></h3> To evaluate the validity of 18F-FDG PET/CT metabolic activity parameter maximum standardized uptake value of the primary tumor (SUVmax-T) to predict locoregional axillary lymph node metastasis (ALNM) in initial staging of BC patients. <b>Materials and Methods:</b> We prospectively studied 40 female patients with different stages pathologically proven breast cancer. All patients were submitted to 18F-FDG PET/CT imaging for their initial tumor staging. The SUVmax-T and SUVmax ALN on 18F-FDGPET/CT were assessed. The patients were categorized into two groups; group I, with positive ALN uptake, and groupII with negative ALN uptake, according to the presence of locoregional 18F-FDG ALN uptake on visual &quantitative analysis of 18F-FDG PET/CT. The correlations and differences between two groups were statistically evaluated. The optimal cut-off value of SUVmax-T was determined. <h3><b>Results:</b></h3> Forty female patients with newly diagnosed BC were included in our study, age range from 31-78 (mean 50.5 +/- SD11.7). All the 1ry tumors were detected with mean SUVmax 10.8(+/-SD 7.9). In the Twenty-Three patients who underwent nodal staging (axillary dissection in 7/23 patients and SLNBs in 16/23 patients.), 13/23 and 10/23 patients were positive and negative for metastases respectively.PET/CT was positive in 27 patients with ALNs; out of them 13 proved true positive, 4 were false positive by histopathology and in the remaining 10 cases no pathology report was available. PET/CT negative axillary cases were 13 out of them 6 were true negative by histopathology and in the remaining 7 cases no pathology report were available. The mean tumor size in group I was significantly greater than that in group II (3.1+/- SD 1 , P value 0.011). The mean SUVmax-T value in group A was significantly higher than that in group B ((Mean 12.7+/- SD 8.6 ,Pvalue 0.016). Tumor stage &nuclear grade in group A was higher than that in group B (P value 0.372, 0.252 respectively). SUVmax -T were significantly moderately positively correlated with the size of the 1ry tumor (<b>rho</b>= 0.328, P value=0.019 . SUVmax -T was predictive of axillary nodal involvement AUC= 0.735(95% CI: 0.577-0.893). The optimal cut-off of SUVmax-T for detecting ALNM was>1.9 gives sensitivity 100% and specificity 92%. with overall sensitivity and specificity of PET/CT for axillary staging was 100 % and 60 %, respectively (P value= 0.006). <h3><b>Conclusions:</b></h3> BC patients with higher FDG SUVmax of primary tumor are at greater risk of concurrent ALNM. Keywords: Breast cancer. FDG PET/CT . SUVmax. Initial staging. Axillary lymph nodal metastasis, prognosis." @default.
• W2023554954 created "2016-06-24" @default.
• W2023554954 creator A5085695534 @default.
• W2023554954 date "1963-04-13" @default.
• W2023554954 modified "2023-09-25" @default.
• W2023554954 title "Indications for Tonsillectomy" @default.
• W2023554954 doi "https://doi.org/10.1136/bmj.1.5336.1023-b" @default.
• W2023554954 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2122900" @default.
• W2023554954 hasPublicationYear "1963" @default.
• W2023554954 type Work @default.
• W2023554954 sameAs 2023554954 @default.
• W2023554954 citedByCount "0" @default.
• W2023554954 crossrefType "journal-article" @default.
• W2023554954 hasAuthorship W2023554954A5085695534 @default.
• W2023554954 hasConcept C121608353 @default.
• W2023554954 hasConcept C126322002 @default.
• W2023554954 hasConcept C126838900 @default.
• W2023554954 hasConcept C141071460 @default.
• W2023554954 hasConcept C199374082 @default.
• W2023554954 hasConcept C2775842073 @default.
• W2023554954 hasConcept C2779013556 @default.
• W2023554954 hasConcept C2779073326 @default.
• W2023554954 hasConcept C2780283643 @default.
• W2023554954 hasConcept C2780849966 @default.
• W2023554954 hasConcept C2908761598 @default.
• W2023554954 hasConcept C2989005 @default.
• W2023554954 hasConcept C530470458 @default.
• W2023554954 hasConcept C71924100 @default.
• W2023554954 hasConceptScore W2023554954C121608353 @default.
• W2023554954 hasConceptScore W2023554954C126322002 @default.
• W2023554954 hasConceptScore W2023554954C126838900 @default.
• W2023554954 hasConceptScore W2023554954C141071460 @default.
• W2023554954 hasConceptScore W2023554954C199374082 @default.
• W2023554954 hasConceptScore W2023554954C2775842073 @default.
• W2023554954 hasConceptScore W2023554954C2779013556 @default.
• W2023554954 hasConceptScore W2023554954C2779073326 @default.
• W2023554954 hasConceptScore W2023554954C2780283643 @default.
• W2023554954 hasConceptScore W2023554954C2780849966 @default.
• W2023554954 hasConceptScore W2023554954C2908761598 @default.
• W2023554954 hasConceptScore W2023554954C2989005 @default.
• W2023554954 hasConceptScore W2023554954C530470458 @default.
• W2023554954 hasConceptScore W2023554954C71924100 @default.
• W2023554954 hasIssue "5336" @default.
• W2023554954 hasLocation W20235549541 @default.
• W2023554954 hasOpenAccess W2023554954 @default.
• W2023554954 hasPrimaryLocation W20235549541 @default.
• W2023554954 hasRelatedWork W1964235690 @default.
• W2023554954 hasRelatedWork W2069054254 @default.
• W2023554954 hasRelatedWork W2069089738 @default.
• W2023554954 hasRelatedWork W2111347914 @default.
• W2023554954 hasRelatedWork W2138033649 @default.
• W2023554954 hasRelatedWork W2156015500 @default.
• W2023554954 hasRelatedWork W2183007308 @default.
• W2023554954 hasRelatedWork W2342100533 @default.
• W2023554954 hasRelatedWork W2963673822 @default.
• W2023554954 hasRelatedWork W3160664391 @default.
• W2023554954 hasVolume "1" @default.
• W2023554954 isParatext "false" @default.
• W2023554954 isRetracted "false" @default.
• W2023554954 magId "2023554954" @default.
• W2023554954 workType "article" @default.