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- W2023556370 abstract "Samples of S1 dorsal root nerve fibers from cats of different pre- and postnatal ages were examined electron microscopically with regard to axon caliber and number of myelin lamellae. Each root was examined at four different cross-sectional levels. Two levels were situation close to the spinal cord entrance on each side of the peripheral (PNS) and central nervous system (CNS) border. The third and fourth levels were located more distally. The first compact myelin lamella was observed in the CNS part of the root in a 47-day-old fetus. In the 53-day-old fetus the degree of myelination was the same in the CNS as distal in the PNS part of the root. Surprisingly, all axons appeared unmyelinated close to the PNS-CNS border and remained so for a further 10-day period. After this time lag, this part of the root became myelinated and showed a rapid increase in myelin sheath thickness. Calculations of axonal growth, mesaxonal length, and myelin volume indicated a maturation process that progressed discontinuously. Myelination did not proceed in a strict somatofugal direction, but was a regionally differentiated process. The maximal myelin production, expressed as the increase in myelin volume per Schwann cell, was found during the second to fourth postnatal months, i.e., very late in development." @default.
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- W2023556370 date "1982-08-10" @default.
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- W2023556370 title "Myelination of S1 dorsal root axons in the cat" @default.
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- W2023556370 doi "https://doi.org/10.1002/cne.902090302" @default.
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