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- W2023559729 abstract "Patients with end-stage renal disease (ESRD), especially those with acquired cystic disease of the kidney (ACDK) secondary to long-term dialysis, are at increased risk for renal cell carcinoma (RCC).1 ACDK usually occurs in 10–20% of patients who have been on dialysis (both peritoneal and hemodialysis) for up to 3 years, in 40–60% up to 5 years, and more than 90% at more than 10 years.2 Approximately 3–7% of patients with ACDK develop RCC with a risk that is reportedly as high as 100 times compared to that in the general population.2 In earlier literature, the most common type of RCC arising in the background of ACDK was considered to be papillary RCC. However, with more extensive analyses, that concept has changed dramatically. Although the usual types of RCC as those seen in the general population can occur in ESRD patients with or without ACDK, the common histologic types of RCC that are associated with ESRD and ACDK nowadays are reported to be two specific variants. One subtype has only been described in patients with ACDK,3,4 and is hence designated “acquired cystic disease (ACD)-associated RCC” in most reports. The other subtype, designated “clear cell papillary RCC”, occurs chiefly in patients with ESRD, not necessarily in the setting of ACDK." @default.
- W2023559729 created "2016-06-24" @default.
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- W2023559729 date "2010-09-01" @default.
- W2023559729 modified "2023-10-16" @default.
- W2023559729 title "Renal Cell Carcinoma Associated With End-stage Renal Disease and Acquired Cystic Disease of the Kidney" @default.
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- W2023559729 doi "https://doi.org/10.1016/s1879-5226(10)60030-9" @default.
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