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- W2023562257 abstract "Exercise intolerance is a common co-morbidity in patients with heart failure (HF), partly due to reduced muscle strength and endurance. A practical assessment that could be used in the cardiac rehabilitation setting to assess this relationship is lacking. PURPOSE: To test the hypothesis that knee extensor muscle strength, as measured by one repetition maximum (1RM) and isokinetic endurance, are related to peak oxygen consumption (pVO2) during treadmill testing in patients with HF. METHODS: Peak VO2 was determined in 19 patients with NYHA class II-III HF and left ventricular ejection fraction <40% during symptom limited treadmill exercise testing. Dominant side knee extensor endurance was tested using an isokinetic dynamometer at 180° per second over 15 maximal repetitions (reps). Endurance percent (%) was computed as the ratio between mean torque for reps 13, 14, and 15 and reps 2, 3, and 4 (× 100). After a 15 minute rest period 1RM isotonic knee extensor strength was assessed. RESULTS: Mean pVO2 was 15.2±3.0 mL-kgmm1, mean 1RM was 46.5±14.3 kg, and mean endurance was 75.5±13.5 %(n=18). Both 1RM strength (r=0.53, SEE=2.6, p=0.02) (Fig. 1) and isokinetic endurance (r=0.64, SEE=2.4, p=0.004) (Fig. 2) were correlated to TM pVO2.FigureCONCLUSION: Based on r2 values (Fig. 1 and 2), mean strength and endurance explain approximately 30–40% of skeletal muscle's contribution to exercise intolerance in patients with HF. The significant correlation between 1RM and pVO2 measured suggests that 1RM represents an accessible and inexpensive means to describe to what extent muscle strength impacts a specific patient's functional capacity. Although isokinetic endurance had a slightly stronger correlation to pVO2, many cardiac rehabilitation centers only have equipment to assess 1RM. Further work is needed to confirm if change in 1RM is related to change in pVO2, and might serve as an outcome marker in the cardiac rehabilitation setting." @default.
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- W2023562257 date "2006-05-01" @default.
- W2023562257 modified "2023-09-25" @default.
- W2023562257 title "Knee Extensor Strength and Endurance Correlate with Peak Treadmill Oxygen Consumption in Heart Failure Patients" @default.
- W2023562257 doi "https://doi.org/10.1249/00005768-200605001-00974" @default.
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