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- W2023562747 abstract "Leukotrienes are potent mediators of local microvascular environment. Leukotriene B 4 treatment of cultured endothelium increases the binding of lymphocytes to endothelial cell monolayers within minutes. This effect is dose‐dependent and reversible upon removal of the leukotriene. Pretreatment of lymphocytes slightly decreases the binding and pretreatment of both lymphocytes and endothelium with leukotriene B 4 prior to the adherence assay did not alter the binding. These results suggest that leukotriene B 4 regulates exclusively the vascular side, but not the white cell side of this interaction." @default.
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- W2023562747 date "1988-08-01" @default.
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- W2023562747 title "Leukotriene B<sub>4</sub> increases the lymphocyte binding to endothelial cells" @default.
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- W2023562747 doi "https://doi.org/10.1016/0014-5793(88)81235-3" @default.
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