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- W2023562794 abstract "WILLIAMSON, J. W., X. SHI, J.-J. CHEN, C. G. CRANDALL, W. G. SQUIRES, L. P. KROCK, and P. B. RAVEN. Aerobic fitness: II. Orthostasis and VO2peak following head-down tilt. Med. Sci. Sports Exerc., Vol. 24, No. 9, pp. 999–1006, 1992. To determine whether endurance exercise trained (ET) subjects would experience greater reductions in peak oxygen delivery and orthostatic tolerance (OT) than untrained (UT) subjects, both peak oxygen uptake (VO2peak) during upright bicycle ergometry and tolerance time during 70° head-up tilt (HUT) were compared within and between groups before and after 4 h of −6° head-down tilt (HDF). Eight ET subjects with a mean V̇O2peak of 61.7 ± 1.6 ml·kg-1·min-1 were matched for age, height, and weight with eight UT subjects (V̇O2peak = 38.4 ± 1.7 ml·kg-1·min-1). Following HDT, decreases in plasma volume (PV) were larger for ET subject (−3.7 ± 0.5 ml·kg-1) than for UT subject (−2.3 ± 0.3 ml·kg-1), P < 0.03. Reductions in V̇O2peak for ET subjects (−5.4 ± 1.1 ml·kg-1·min-1) were also greater than for UT subjects (−2.4 ± 0.8 ml·kg·min-1), P < 0.05. The ET (N = 6) subjects also had a significant decrease in OT time (−13 0 ± 4.2 min) during post-HDT HUT, which was not observed for the UT group (N = 6). A significant inverse correlation was found pre-HDT V̇O2peak and the change in OT time, r = −0.74, P < 0.01. The decrease in OT was also significantly correlated to the PV decrease, r = 0.59, P < 0.04. The UT subjects had significantly augmented pressor responses to HUT manifested by the increases in both HR and MAP following HDT. However, after HDT, the ET subjects failed to demonstrate an immediate increase in HR with the initiation of HUT. These data suggest that ET individuals may experience a greater PV loss than UT individuals following acute simulation of microgravity. The greater reduction in PV may also explain the greater reductions in both V̇O2peak and OT experienced by the ET subjects following 4 h of HDT." @default.
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- W2023562794 date "1992-09-01" @default.
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- W2023562794 title "Aerobic fitness" @default.
- W2023562794 doi "https://doi.org/10.1249/00005768-199209000-00008" @default.
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