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- W2023570041 abstract "Case I. A 49-year-old woman underwent a mitral commissurotomy in 1977 for mitral stenosis. She was admitted because of syncope. Three months earlier, she began therapy with oral amiodarone (600 mg/day) for control of supraventricular arrhythmia. Two months later, in the absence of hypokalemia, an electrocardiogram (ECG) showed a long QTc interval (600 ms) with a normal QRS duration. Fifteen days before admission, clorthalidone (100 mg every 2 days) was added to amiodarone for mild systemic hypertension. Fifteen days later, syncope due to unusual ventricular tachyarrhythmia occurred (Fig. 1 and 2). At that time the serum potassium level was 3.2 mEq/liter and the tests of thyroid function had normal results. Amiodarone was discontinued. After arrhythmia conversion by intravenous mexiletine, a prolonged QT/U interval (600 ms) was evident." @default.
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- W2023570041 date "1984-05-01" @default.
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- W2023570041 title "Ventricular tachyarrhythmias complicating amiodarone therapy in the presence of hypokalemia" @default.
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- W2023570041 doi "https://doi.org/10.1016/s0002-9149(84)91293-1" @default.
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