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• W2023571495 abstract "Purpose/Objective(s)To determine if alignment correction vectors obtained from an ultrasound (US) based system are of equivalent accuracy to orthogonal x-ray imaging for daily prostate positioning.Materials/MethodsProstate patients were positioned for daily treatment utilizing external skin marks (tattoos). They were then aligned to internal anatomy via orthogonal x-ray, utilizing previously implanted interstitial fiducial markers. X-ray images were aligned utilizing contours made during planning, also ensuring that surrounding boney anatomy complied with standard protocol. Eleven patients received a trans-abdominal ultrasound (US) in addition to the standard daily x-ray. Acquisition of the US images was performed simultaneously during the x-ray alignment process. Both x-ray and US images were saved and stored for analysis.ResultsFrom the 238 fractions, 1127 US measurements and 1127 x-ray measurements were analyzed. Average standard deviations produced by x-ray were compared to those produced by US for each of the 11 patients. With all three vectors (X, Y, and Z) there were no statistically significant correlations seen. The correlation coefficient for the X vector comparison was 0.24 with a p value of 0.47; for Y, the correlation coefficient was 0.08 with a p value of 0.80; and for Z, the correlation coefficient was 0.11 with a p value of 0.33. The average difference between x-ray and US was 0.07 (±1.05) cm (X), 0.22 (±1.44) cm (Y), -0.23 (±0.55) cm (Z). The average difference between rotations versus no rotations for was 0.00 (±0.10) cm (X), 0.00 (±0.11) cm (Y), -0.02 (±0.15) cm (Z). The average difference between x-ray and US was 0.07 (±1.05) cm (X), 0.22 (±1.44) cm (Y), -0.23 (±0.55) cm (Z).ConclusionsCorrection vectors from the US system did not correlate to the correction vectors obtained from the X-ray system using fiducial markers and x-ray alignment. For x-ray/fiducial imaging, the mean difference between the rotations versus no-rotations coordinates was negligible. The largest standard deviation was 1.5 mm in the Y coordinate. Corrections in the X,Y, and Z directions are sufficient; rotational corrections did not add to precision of treatment localization. Overall, the method of positioning patients using fiducial markers and x-rays appeared to be more practical than the US system. Purpose/Objective(s)To determine if alignment correction vectors obtained from an ultrasound (US) based system are of equivalent accuracy to orthogonal x-ray imaging for daily prostate positioning. To determine if alignment correction vectors obtained from an ultrasound (US) based system are of equivalent accuracy to orthogonal x-ray imaging for daily prostate positioning. Materials/MethodsProstate patients were positioned for daily treatment utilizing external skin marks (tattoos). They were then aligned to internal anatomy via orthogonal x-ray, utilizing previously implanted interstitial fiducial markers. X-ray images were aligned utilizing contours made during planning, also ensuring that surrounding boney anatomy complied with standard protocol. Eleven patients received a trans-abdominal ultrasound (US) in addition to the standard daily x-ray. Acquisition of the US images was performed simultaneously during the x-ray alignment process. Both x-ray and US images were saved and stored for analysis. Prostate patients were positioned for daily treatment utilizing external skin marks (tattoos). They were then aligned to internal anatomy via orthogonal x-ray, utilizing previously implanted interstitial fiducial markers. X-ray images were aligned utilizing contours made during planning, also ensuring that surrounding boney anatomy complied with standard protocol. Eleven patients received a trans-abdominal ultrasound (US) in addition to the standard daily x-ray. Acquisition of the US images was performed simultaneously during the x-ray alignment process. Both x-ray and US images were saved and stored for analysis. ResultsFrom the 238 fractions, 1127 US measurements and 1127 x-ray measurements were analyzed. Average standard deviations produced by x-ray were compared to those produced by US for each of the 11 patients. With all three vectors (X, Y, and Z) there were no statistically significant correlations seen. The correlation coefficient for the X vector comparison was 0.24 with a p value of 0.47; for Y, the correlation coefficient was 0.08 with a p value of 0.80; and for Z, the correlation coefficient was 0.11 with a p value of 0.33. The average difference between x-ray and US was 0.07 (±1.05) cm (X), 0.22 (±1.44) cm (Y), -0.23 (±0.55) cm (Z). The average difference between rotations versus no rotations for was 0.00 (±0.10) cm (X), 0.00 (±0.11) cm (Y), -0.02 (±0.15) cm (Z). The average difference between x-ray and US was 0.07 (±1.05) cm (X), 0.22 (±1.44) cm (Y), -0.23 (±0.55) cm (Z). From the 238 fractions, 1127 US measurements and 1127 x-ray measurements were analyzed. Average standard deviations produced by x-ray were compared to those produced by US for each of the 11 patients. With all three vectors (X, Y, and Z) there were no statistically significant correlations seen. The correlation coefficient for the X vector comparison was 0.24 with a p value of 0.47; for Y, the correlation coefficient was 0.08 with a p value of 0.80; and for Z, the correlation coefficient was 0.11 with a p value of 0.33. The average difference between x-ray and US was 0.07 (±1.05) cm (X), 0.22 (±1.44) cm (Y), -0.23 (±0.55) cm (Z). The average difference between rotations versus no rotations for was 0.00 (±0.10) cm (X), 0.00 (±0.11) cm (Y), -0.02 (±0.15) cm (Z). The average difference between x-ray and US was 0.07 (±1.05) cm (X), 0.22 (±1.44) cm (Y), -0.23 (±0.55) cm (Z). ConclusionsCorrection vectors from the US system did not correlate to the correction vectors obtained from the X-ray system using fiducial markers and x-ray alignment. For x-ray/fiducial imaging, the mean difference between the rotations versus no-rotations coordinates was negligible. The largest standard deviation was 1.5 mm in the Y coordinate. Corrections in the X,Y, and Z directions are sufficient; rotational corrections did not add to precision of treatment localization. Overall, the method of positioning patients using fiducial markers and x-rays appeared to be more practical than the US system. Correction vectors from the US system did not correlate to the correction vectors obtained from the X-ray system using fiducial markers and x-ray alignment. For x-ray/fiducial imaging, the mean difference between the rotations versus no-rotations coordinates was negligible. The largest standard deviation was 1.5 mm in the Y coordinate. Corrections in the X,Y, and Z directions are sufficient; rotational corrections did not add to precision of treatment localization. Overall, the method of positioning patients using fiducial markers and x-rays appeared to be more practical than the US system." @default.
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• W2023571495 date "2014-09-01" @default.
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• W2023571495 title "A Prospective Trial of kV Stereoscopic X-Rays With Fiducials Versus Ultrasound for Daily Image Guidance in Prostate Cancer" @default.
• W2023571495 doi "https://doi.org/10.1016/j.ijrobp.2014.05.2431" @default.
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