FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023571599> ?p ?o ?g. }

• W2023571599 endingPage "2163" @default.
• W2023571599 startingPage "2155" @default.
• W2023571599 abstract "The natriuretic peptide (NP) family consists of multiple subtypes in teleosts, including atrial, B-type, ventricular, and C-type NPs (ANP, BNP, VNP, CNP-1-4, respectively), but only ANP, BNP, CNP-3, and CNP-4 have been identified in tetrapods. As part of understanding the molecular evolution of NPs in the tetrapod lineage, we identified NP genes in the chicken genome. Previously, only BNP and CNP-3 have been identified in birds, but we characterized two new chicken NP genes by cDNA cloning, synteny and phylogenetic analyses. One gene is an orthologue of CNP-1, which has only ever been reported in teleostei and bichir. The second gene could not be assigned to a particular NP subtype because of high sequence divergence and was named renal NP (RNP) due to its predominant expression in the kidney. CNP-1 mRNA was only detected in brain, while CNP-3 mRNA was expressed in kidney, heart, and brain. In the developing embryo, BNP and RNP transcripts were most abundant 24h post-fertilization, while CNP mRNA increased in a stage-dependent manner. Synthetic chicken RNP stimulated an increase in cGMP production above basal level in chicken kidney membrane preparations and caused a potent dose-dependent vasodilation of pre-constricted dorsal aortic rings. From conserved chromosomal synteny, we propose that the CNP-4 and ANP genes have been lost in chicken, and that RNP may have evolved from a VNP-like gene. Furthermore, we have demonstrated for the first time that CNP-1 is retained in the tetrapod lineage." @default.
• W2023571599 created "2016-06-24" @default.
• W2023571599 creator A5007801419 @default.
• W2023571599 creator A5040646045 @default.
• W2023571599 creator A5055856831 @default.
• W2023571599 creator A5084584080 @default.
• W2023571599 date "2007-11-01" @default.
• W2023571599 modified "2023-10-02" @default.
• W2023571599 title "Genomic analyses and cloning of novel chicken natriuretic peptide genes reveal new insights into natriuretic peptide evolution" @default.
• W2023571599 cites W1913973901 @default.
• W2023571599 cites W1959331591 @default.
• W2023571599 cites W1964272546 @default.
• W2023571599 cites W1971457690 @default.
• W2023571599 cites W1989419353 @default.
• W2023571599 cites W2001288055 @default.
• W2023571599 cites W2016320220 @default.
• W2023571599 cites W2018609576 @default.
• W2023571599 cites W2023419955 @default.
• W2023571599 cites W2024667090 @default.
• W2023571599 cites W2028465506 @default.
• W2023571599 cites W2038699628 @default.
• W2023571599 cites W2055043387 @default.
• W2023571599 cites W2060460830 @default.
• W2023571599 cites W2071969091 @default.
• W2023571599 cites W2073707852 @default.
• W2023571599 cites W2074388931 @default.
• W2023571599 cites W2076502913 @default.
• W2023571599 cites W2085864418 @default.
• W2023571599 cites W2094047407 @default.
• W2023571599 cites W2106882534 @default.
• W2023571599 cites W2109606027 @default.
• W2023571599 cites W2132106701 @default.
• W2023571599 cites W2140034535 @default.
• W2023571599 cites W2143762867 @default.
• W2023571599 cites W2144583900 @default.
• W2023571599 cites W2146488738 @default.
• W2023571599 cites W2148557777 @default.
• W2023571599 cites W2152802769 @default.
• W2023571599 cites W2161746138 @default.
• W2023571599 cites W4235866023 @default.
• W2023571599 cites W4294216491 @default.
• W2023571599 doi "https://doi.org/10.1016/j.peptides.2007.08.017" @default.
• W2023571599 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17905479" @default.
• W2023571599 hasPublicationYear "2007" @default.
• W2023571599 type Work @default.
• W2023571599 sameAs 2023571599 @default.
• W2023571599 citedByCount "25" @default.
• W2023571599 countsByYear W20235715992013 @default.
• W2023571599 countsByYear W20235715992014 @default.
• W2023571599 countsByYear W20235715992015 @default.
• W2023571599 countsByYear W20235715992016 @default.
• W2023571599 countsByYear W20235715992018 @default.
• W2023571599 countsByYear W20235715992019 @default.
• W2023571599 countsByYear W20235715992021 @default.
• W2023571599 countsByYear W20235715992022 @default.
• W2023571599 crossrefType "journal-article" @default.
• W2023571599 hasAuthorship W2023571599A5007801419 @default.
• W2023571599 hasAuthorship W2023571599A5040646045 @default.
• W2023571599 hasAuthorship W2023571599A5055856831 @default.
• W2023571599 hasAuthorship W2023571599A5084584080 @default.
• W2023571599 hasConcept C104317684 @default.
• W2023571599 hasConcept C126322002 @default.
• W2023571599 hasConcept C134018914 @default.
• W2023571599 hasConcept C141231307 @default.
• W2023571599 hasConcept C153911025 @default.
• W2023571599 hasConcept C187882448 @default.
• W2023571599 hasConcept C2775915353 @default.
• W2023571599 hasConcept C2776817793 @default.
• W2023571599 hasConcept C2778069365 @default.
• W2023571599 hasConcept C2778198053 @default.
• W2023571599 hasConcept C53702515 @default.
• W2023571599 hasConcept C54355233 @default.
• W2023571599 hasConcept C71924100 @default.
• W2023571599 hasConcept C86803240 @default.
• W2023571599 hasConceptScore W2023571599C104317684 @default.
• W2023571599 hasConceptScore W2023571599C126322002 @default.
• W2023571599 hasConceptScore W2023571599C134018914 @default.
• W2023571599 hasConceptScore W2023571599C141231307 @default.
• W2023571599 hasConceptScore W2023571599C153911025 @default.
• W2023571599 hasConceptScore W2023571599C187882448 @default.
• W2023571599 hasConceptScore W2023571599C2775915353 @default.
• W2023571599 hasConceptScore W2023571599C2776817793 @default.
• W2023571599 hasConceptScore W2023571599C2778069365 @default.
• W2023571599 hasConceptScore W2023571599C2778198053 @default.
• W2023571599 hasConceptScore W2023571599C53702515 @default.
• W2023571599 hasConceptScore W2023571599C54355233 @default.
• W2023571599 hasConceptScore W2023571599C71924100 @default.
• W2023571599 hasConceptScore W2023571599C86803240 @default.
• W2023571599 hasIssue "11" @default.
• W2023571599 hasLocation W20235715991 @default.
• W2023571599 hasLocation W20235715992 @default.
• W2023571599 hasOpenAccess W2023571599 @default.
• W2023571599 hasPrimaryLocation W20235715991 @default.
• W2023571599 hasRelatedWork W1970446704 @default.
• W2023571599 hasRelatedWork W2002038679 @default.
• W2023571599 hasRelatedWork W2043879443 @default.
• W2023571599 hasRelatedWork W2049832880 @default.
• W2023571599 hasRelatedWork W2098870266 @default.

• next