Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023572091> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2023572091 endingPage "353" @default.
- W2023572091 startingPage "347" @default.
- W2023572091 abstract "Vitacel M80K, a cellulose powder coated with 2% colloidal silica, is a recently developed direct compressible vehicle (DCV). The aim of this study is to investigate the performance of M80K, in comparison with: a laboratory prepared vehicle (ELC+) consisting of a mixture of Elcema P050 (ELC) and 2% Aerosil, and a microcrystalline cellulose (MCC), Avicel PH 101 (Avicel). Bulk density, flow and surface characteristics of the DCVs were determined. Tablets were prepared by direct compression using various drugs; ascorbic acid (fine and coarse crystals), cimetidine, and paracetamol. Tablets prepared with M80K showed less weight variation than those prepared with Avicel. Ascorbic acid-Avicel tablets were slightly harder than those with M80K. However, in the presence of either cimetidine or paracetamol, M80K resulted in the production of tablets with maximum hardness. In most cases, except with paracetamol, M80K produced tablets with slightly higher friability in comparison to Avicel, while ELC+ showed maximum friability. M80K-paracetamol tablets showed the minimum friability values and highest hardness sensitivity towards increase of the applied compression force between 5 and 35 kN. M80K-containing formulations showed better hardness tolerance upon the addition of magnesium stearate. Disintegration times for most tablets were relatively short (<5 min)." @default.
- W2023572091 created "2016-06-24" @default.
- W2023572091 creator A5004253344 @default.
- W2023572091 creator A5040806971 @default.
- W2023572091 date "1998-11-01" @default.
- W2023572091 modified "2023-09-25" @default.
- W2023572091 title "Evaluation of Vitacel M80K as a new direct compressible vehicle" @default.
- W2023572091 cites W1970873302 @default.
- W2023572091 cites W1974712868 @default.
- W2023572091 cites W1985258184 @default.
- W2023572091 cites W1993128812 @default.
- W2023572091 cites W2061007490 @default.
- W2023572091 cites W2067618345 @default.
- W2023572091 cites W2071324038 @default.
- W2023572091 cites W2154823065 @default.
- W2023572091 doi "https://doi.org/10.1016/s0939-6411(98)00042-3" @default.
- W2023572091 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9885308" @default.
- W2023572091 hasPublicationYear "1998" @default.
- W2023572091 type Work @default.
- W2023572091 sameAs 2023572091 @default.
- W2023572091 citedByCount "11" @default.
- W2023572091 countsByYear W20235720912012 @default.
- W2023572091 countsByYear W20235720912015 @default.
- W2023572091 countsByYear W20235720912016 @default.
- W2023572091 countsByYear W20235720912017 @default.
- W2023572091 crossrefType "journal-article" @default.
- W2023572091 hasAuthorship W2023572091A5004253344 @default.
- W2023572091 hasAuthorship W2023572091A5040806971 @default.
- W2023572091 hasConcept C121332964 @default.
- W2023572091 hasConcept C13965031 @default.
- W2023572091 hasConcept C159985019 @default.
- W2023572091 hasConcept C178790620 @default.
- W2023572091 hasConcept C185592680 @default.
- W2023572091 hasConcept C191168616 @default.
- W2023572091 hasConcept C192562407 @default.
- W2023572091 hasConcept C2776035855 @default.
- W2023572091 hasConcept C2778572730 @default.
- W2023572091 hasConcept C2779251873 @default.
- W2023572091 hasConcept C2779351475 @default.
- W2023572091 hasConcept C2779849058 @default.
- W2023572091 hasConcept C2986274086 @default.
- W2023572091 hasConcept C3020410207 @default.
- W2023572091 hasConcept C31903555 @default.
- W2023572091 hasConcept C43617362 @default.
- W2023572091 hasConcept C521977710 @default.
- W2023572091 hasConcept C57879066 @default.
- W2023572091 hasConcept C77281830 @default.
- W2023572091 hasConcept C88463166 @default.
- W2023572091 hasConceptScore W2023572091C121332964 @default.
- W2023572091 hasConceptScore W2023572091C13965031 @default.
- W2023572091 hasConceptScore W2023572091C159985019 @default.
- W2023572091 hasConceptScore W2023572091C178790620 @default.
- W2023572091 hasConceptScore W2023572091C185592680 @default.
- W2023572091 hasConceptScore W2023572091C191168616 @default.
- W2023572091 hasConceptScore W2023572091C192562407 @default.
- W2023572091 hasConceptScore W2023572091C2776035855 @default.
- W2023572091 hasConceptScore W2023572091C2778572730 @default.
- W2023572091 hasConceptScore W2023572091C2779251873 @default.
- W2023572091 hasConceptScore W2023572091C2779351475 @default.
- W2023572091 hasConceptScore W2023572091C2779849058 @default.
- W2023572091 hasConceptScore W2023572091C2986274086 @default.
- W2023572091 hasConceptScore W2023572091C3020410207 @default.
- W2023572091 hasConceptScore W2023572091C31903555 @default.
- W2023572091 hasConceptScore W2023572091C43617362 @default.
- W2023572091 hasConceptScore W2023572091C521977710 @default.
- W2023572091 hasConceptScore W2023572091C57879066 @default.
- W2023572091 hasConceptScore W2023572091C77281830 @default.
- W2023572091 hasConceptScore W2023572091C88463166 @default.
- W2023572091 hasIssue "3" @default.
- W2023572091 hasLocation W20235720911 @default.
- W2023572091 hasLocation W20235720912 @default.
- W2023572091 hasOpenAccess W2023572091 @default.
- W2023572091 hasPrimaryLocation W20235720911 @default.
- W2023572091 hasRelatedWork W2023572091 @default.
- W2023572091 hasRelatedWork W2052665390 @default.
- W2023572091 hasRelatedWork W2087356398 @default.
- W2023572091 hasRelatedWork W2126493555 @default.
- W2023572091 hasRelatedWork W2620334691 @default.
- W2023572091 hasRelatedWork W2765509088 @default.
- W2023572091 hasRelatedWork W2769854762 @default.
- W2023572091 hasRelatedWork W3143966617 @default.
- W2023572091 hasRelatedWork W4381951465 @default.
- W2023572091 hasRelatedWork W4386317666 @default.
- W2023572091 hasVolume "46" @default.
- W2023572091 isParatext "false" @default.
- W2023572091 isRetracted "false" @default.
- W2023572091 magId "2023572091" @default.
- W2023572091 workType "article" @default.