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- W2023572812 abstract "A group of 17 men and 3 women with genital warts in which DNA/RNA phenotyping was performed were treated with intralesional interferon alpha-2a (1 MU/cm2) three times weekly for 3 weeks. Treatment was followed by a 16-week observation period. Interferon alpha-2a treatment resulted in a highly significant reduction in the mean size of the warts, which decreased from an initial size of 37 mm2 to 4–5 mm2 by week 16 (P < 0.05). The response appeared to depend on the human papillomavirus (HPV) genotype. Patients with types 6 or 11 showed good responses in 11 of the 12 cases. The response in HPV types 16 and 18 infection was poor in 4 of the 8 cases. During follow-up (mean 4 months) no recurrence was observed. Intralesional treatment showed minimal side-effects. We conclude that intralesional interferon alpha-2a is useful in the treatment of genital warts caused by HPV of types 6 and 11." @default.
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- W2023572812 date "1994-01-01" @default.
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- W2023572812 title "Treatment with intralesional interferon alpha-2a of genital warts with human papillomavirus genotyping" @default.
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- W2023572812 doi "https://doi.org/10.3109/09546639409080573" @default.
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