FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023586031> ?p ?o ?g. }

• W2023586031 endingPage "6" @default.
• W2023586031 startingPage "1" @default.
• W2023586031 abstract "Resected pancreatic cancer has a high risk of recurrence and mortality despite the the use of chemoradiotherapy. Because pancreatic cancers express tumor antigens such as carcinoembryonic antigen (CEA), it may be possible to immunize patients to induce tumor antigen-specific immune responses. We hypothesize that high-frequency tumor antigen-specific immune responses will reduce recurrence and increase survival. Autologous dendritic cells (DCs) loaded with tumor antigens are particularly potent at inducing tumor antigen-specific immune responses.Three patients with resected pancreatic adenocarcinoma following neoadjuvant chemoradiotherapy received autologous, monocyte-derived DCs loaded with the mRNA encoding CEA monthly for 6 mo.It was feasible to generate an adequate number of DC from these patients and to cryopreserve them for repeated use. The DC demonstrated the typical immature phenotype. The immunizations were well-tolerated without evidence of adverse events. All three developed injection site reactivity. All three are alive without evidence of disease at more than 2 1/2 yr from the original diagnosis.The postoperative period following neoadjuvant chemoradiotherapy and pancreaticoduodenectomy for pancreatic cancer is an ideal environment to test novel immune-based therapies. DC-based immunotherapy in this setting is safe and feasible and may lead to prolonged survival." @default.
• W2023586031 created "2016-06-24" @default.
• W2023586031 creator A5002385344 @default.
• W2023586031 creator A5012804507 @default.
• W2023586031 creator A5013753246 @default.
• W2023586031 creator A5015827608 @default.
• W2023586031 creator A5028156079 @default.
• W2023586031 creator A5046311492 @default.
• W2023586031 creator A5051436334 @default.
• W2023586031 creator A5059931764 @default.
• W2023586031 creator A5068892519 @default.
• W2023586031 creator A5074731037 @default.
• W2023586031 date "2002-01-01" @default.
• W2023586031 modified "2023-09-27" @default.
• W2023586031 title "The Feasibility and Safety of Immunotherapy with Dendritic Cells Loaded with CEA mRNA Following Neoadjuvant Chemoradiotherapy and Resection of Pancreatic Cancer" @default.
• W2023586031 cites W1493538138 @default.
• W2023586031 cites W1988604479 @default.
• W2023586031 cites W1991167336 @default.
• W2023586031 cites W2010340952 @default.
• W2023586031 cites W2013100454 @default.
• W2023586031 cites W2019061327 @default.
• W2023586031 cites W2035854897 @default.
• W2023586031 cites W2073304595 @default.
• W2023586031 cites W2076730875 @default.
• W2023586031 cites W2124757685 @default.
• W2023586031 cites W2137648390 @default.
• W2023586031 cites W2170055192 @default.
• W2023586031 cites W2312051539 @default.
• W2023586031 cites W4231399398 @default.
• W2023586031 doi "https://doi.org/10.1385/ijgc:32:1:1" @default.
• W2023586031 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12630764" @default.
• W2023586031 hasPublicationYear "2002" @default.
• W2023586031 type Work @default.
• W2023586031 sameAs 2023586031 @default.
• W2023586031 citedByCount "87" @default.
• W2023586031 countsByYear W20235860312012 @default.
• W2023586031 countsByYear W20235860312013 @default.
• W2023586031 countsByYear W20235860312014 @default.
• W2023586031 countsByYear W20235860312015 @default.
• W2023586031 countsByYear W20235860312016 @default.
• W2023586031 countsByYear W20235860312018 @default.
• W2023586031 countsByYear W20235860312019 @default.
• W2023586031 countsByYear W20235860312020 @default.
• W2023586031 countsByYear W20235860312021 @default.
• W2023586031 countsByYear W20235860312022 @default.
• W2023586031 countsByYear W20235860312023 @default.
• W2023586031 crossrefType "journal-article" @default.
• W2023586031 hasAuthorship W2023586031A5002385344 @default.
• W2023586031 hasAuthorship W2023586031A5012804507 @default.
• W2023586031 hasAuthorship W2023586031A5013753246 @default.
• W2023586031 hasAuthorship W2023586031A5015827608 @default.
• W2023586031 hasAuthorship W2023586031A5028156079 @default.
• W2023586031 hasAuthorship W2023586031A5046311492 @default.
• W2023586031 hasAuthorship W2023586031A5051436334 @default.
• W2023586031 hasAuthorship W2023586031A5059931764 @default.
• W2023586031 hasAuthorship W2023586031A5068892519 @default.
• W2023586031 hasAuthorship W2023586031A5074731037 @default.
• W2023586031 hasConcept C121608353 @default.
• W2023586031 hasConcept C126322002 @default.
• W2023586031 hasConcept C143998085 @default.
• W2023586031 hasConcept C147483822 @default.
• W2023586031 hasConcept C203014093 @default.
• W2023586031 hasConcept C2777387746 @default.
• W2023586031 hasConcept C2777701055 @default.
• W2023586031 hasConcept C2778170410 @default.
• W2023586031 hasConcept C2778292576 @default.
• W2023586031 hasConcept C2778424827 @default.
• W2023586031 hasConcept C2778494859 @default.
• W2023586031 hasConcept C2778764654 @default.
• W2023586031 hasConcept C2780210213 @default.
• W2023586031 hasConcept C2781182431 @default.
• W2023586031 hasConcept C502942594 @default.
• W2023586031 hasConcept C509974204 @default.
• W2023586031 hasConcept C530470458 @default.
• W2023586031 hasConcept C71924100 @default.
• W2023586031 hasConcept C8891405 @default.
• W2023586031 hasConceptScore W2023586031C121608353 @default.
• W2023586031 hasConceptScore W2023586031C126322002 @default.
• W2023586031 hasConceptScore W2023586031C143998085 @default.
• W2023586031 hasConceptScore W2023586031C147483822 @default.
• W2023586031 hasConceptScore W2023586031C203014093 @default.
• W2023586031 hasConceptScore W2023586031C2777387746 @default.
• W2023586031 hasConceptScore W2023586031C2777701055 @default.
• W2023586031 hasConceptScore W2023586031C2778170410 @default.
• W2023586031 hasConceptScore W2023586031C2778292576 @default.
• W2023586031 hasConceptScore W2023586031C2778424827 @default.
• W2023586031 hasConceptScore W2023586031C2778494859 @default.
• W2023586031 hasConceptScore W2023586031C2778764654 @default.
• W2023586031 hasConceptScore W2023586031C2780210213 @default.
• W2023586031 hasConceptScore W2023586031C2781182431 @default.
• W2023586031 hasConceptScore W2023586031C502942594 @default.
• W2023586031 hasConceptScore W2023586031C509974204 @default.
• W2023586031 hasConceptScore W2023586031C530470458 @default.
• W2023586031 hasConceptScore W2023586031C71924100 @default.
• W2023586031 hasConceptScore W2023586031C8891405 @default.
• W2023586031 hasIssue "1" @default.
• W2023586031 hasLocation W20235860311 @default.
• W2023586031 hasLocation W20235860312 @default.

• next