FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023587480> ?p ?o ?g. }

• W2023587480 endingPage "1401" @default.
• W2023587480 startingPage "1401" @default.
• W2023587480 abstract "The self-assembly of a hydrophobically modified fragment of the amyloid β (Aβ) peptide has been studied in methanol. The peptide FFKLVFF is based on Aβ(16–20) extended at the N terminus by two phenylalanine residues. The formation of amyloid-type fibrils is confirmed by Congo Red staining, thioflavin T fluorescence and circular dichroism experiments. FTIR points to the formation of β-sheet structures in solution and in dried films and suggests that aggregation occurs at low concentration and is not strongly affected by further increase in concentration, i.e. the peptide is a strong fibril-former in methanol. UV fluorescence experiments on unstained peptide and CD point to the importance of aromatic interactions between phenylalanine groups in driving aggregation into β-sheets. The CD spectrum differs from that usually observed for β-sheet assemblies formed by larger peptides or proteins and this is discussed for solutions in methanol and also trifluoroethanol. The fibril structure is imaged by transmission electron microscopy and scanning electron microscopy on dried samples and is confirmed by small-angle X-ray scattering experiments in solution." @default.
• W2023587480 created "2016-06-24" @default.
• W2023587480 creator A5040754251 @default.
• W2023587480 creator A5064854739 @default.
• W2023587480 creator A5065494652 @default.
• W2023587480 date "2007-01-01" @default.
• W2023587480 modified "2023-09-27" @default.
• W2023587480 title "Fibrillisation of hydrophobically modified amyloid peptide fragments in an organic solvent" @default.
• W2023587480 cites W1974869432 @default.
• W2023587480 cites W1978314140 @default.
• W2023587480 cites W1997823258 @default.
• W2023587480 cites W1999213903 @default.
• W2023587480 cites W2018769240 @default.
• W2023587480 cites W2027839322 @default.
• W2023587480 cites W2034254998 @default.
• W2023587480 cites W2039069312 @default.
• W2023587480 cites W2057709942 @default.
• W2023587480 cites W2061521002 @default.
• W2023587480 cites W2061627162 @default.
• W2023587480 cites W2072327749 @default.
• W2023587480 cites W2086272648 @default.
• W2023587480 cites W2087748229 @default.
• W2023587480 cites W2092887599 @default.
• W2023587480 cites W2135489500 @default.
• W2023587480 cites W2136470366 @default.
• W2023587480 cites W2140389961 @default.
• W2023587480 cites W2142692094 @default.
• W2023587480 cites W2146610745 @default.
• W2023587480 cites W2154721456 @default.
• W2023587480 cites W2160564267 @default.
• W2023587480 cites W2161453624 @default.
• W2023587480 cites W2165383180 @default.
• W2023587480 cites W2749203687 @default.
• W2023587480 doi "https://doi.org/10.1039/b709889h" @default.
• W2023587480 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32900120" @default.
• W2023587480 hasPublicationYear "2007" @default.
• W2023587480 type Work @default.
• W2023587480 sameAs 2023587480 @default.
• W2023587480 citedByCount "82" @default.
• W2023587480 countsByYear W20235874802012 @default.
• W2023587480 countsByYear W20235874802013 @default.
• W2023587480 countsByYear W20235874802014 @default.
• W2023587480 countsByYear W20235874802015 @default.
• W2023587480 countsByYear W20235874802016 @default.
• W2023587480 countsByYear W20235874802017 @default.
• W2023587480 countsByYear W20235874802018 @default.
• W2023587480 countsByYear W20235874802019 @default.
• W2023587480 countsByYear W20235874802020 @default.
• W2023587480 countsByYear W20235874802021 @default.
• W2023587480 countsByYear W20235874802022 @default.
• W2023587480 countsByYear W20235874802023 @default.
• W2023587480 crossrefType "journal-article" @default.
• W2023587480 hasAuthorship W2023587480A5040754251 @default.
• W2023587480 hasAuthorship W2023587480A5064854739 @default.
• W2023587480 hasAuthorship W2023587480A5065494652 @default.
• W2023587480 hasBestOaLocation W20235874802 @default.
• W2023587480 hasConcept C115260700 @default.
• W2023587480 hasConcept C120665830 @default.
• W2023587480 hasConcept C121332964 @default.
• W2023587480 hasConcept C133571119 @default.
• W2023587480 hasConcept C142089489 @default.
• W2023587480 hasConcept C142724271 @default.
• W2023587480 hasConcept C146088050 @default.
• W2023587480 hasConcept C14631669 @default.
• W2023587480 hasConcept C150394285 @default.
• W2023587480 hasConcept C155672457 @default.
• W2023587480 hasConcept C159547669 @default.
• W2023587480 hasConcept C166029249 @default.
• W2023587480 hasConcept C171250308 @default.
• W2023587480 hasConcept C178790620 @default.
• W2023587480 hasConcept C179104552 @default.
• W2023587480 hasConcept C185592680 @default.
• W2023587480 hasConcept C192562407 @default.
• W2023587480 hasConcept C27523624 @default.
• W2023587480 hasConcept C2777633098 @default.
• W2023587480 hasConcept C2778896982 @default.
• W2023587480 hasConcept C2779134260 @default.
• W2023587480 hasConcept C2779155187 @default.
• W2023587480 hasConcept C2779281246 @default.
• W2023587480 hasConcept C2780471494 @default.
• W2023587480 hasConcept C502032728 @default.
• W2023587480 hasConcept C55493867 @default.
• W2023587480 hasConcept C62520636 @default.
• W2023587480 hasConcept C62614982 @default.
• W2023587480 hasConcept C71924100 @default.
• W2023587480 hasConcept C8010536 @default.
• W2023587480 hasConcept C91881484 @default.
• W2023587480 hasConcept C93877712 @default.
• W2023587480 hasConceptScore W2023587480C115260700 @default.
• W2023587480 hasConceptScore W2023587480C120665830 @default.
• W2023587480 hasConceptScore W2023587480C121332964 @default.
• W2023587480 hasConceptScore W2023587480C133571119 @default.
• W2023587480 hasConceptScore W2023587480C142089489 @default.
• W2023587480 hasConceptScore W2023587480C142724271 @default.
• W2023587480 hasConceptScore W2023587480C146088050 @default.
• W2023587480 hasConceptScore W2023587480C14631669 @default.
• W2023587480 hasConceptScore W2023587480C150394285 @default.
• W2023587480 hasConceptScore W2023587480C155672457 @default.

• next