FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023593630> ?p ?o ?g. }

• W2023593630 endingPage "1958" @default.
• W2023593630 startingPage "1953" @default.
• W2023593630 abstract "Our aim was to measure the cardiac phosphocreatine to adenosine triphosphate ratio (PCr/ATP) noninvasively in patients and carriers of Xp21 muscular dystrophy and to correlate the results with left ventricular (LV) function as measured by echocardiography.Duchenne and Becker muscular dystrophy (the Xp21 dystrophies) are associated with the absence or altered expression of dystrophin in cardiac and skeletal muscles. They are frequently complicated by cardiac hypertrophy and dilated cardiomyopathy. The main role of dystrophin is believed to be structural, but it may also be involved in signaling processes. Defects in energy metabolism have been found in skeletal muscle in patients with Xp21 muscular dystrophy. We therefore hypothesized that a defect in energy metabolism may be part of the mechanism leading to the cardiomyopathy of Xp21 muscular dystrophy.Thirteen men with Becker muscular dystrophy, 10 female carriers and 23 control subjects were studied using phosphorus-31 magnetic resonance spectroscopy and echocardiography.The PCr/ATP was significantly reduced in patients (1.55+/-0.37) and carriers (1.37+/-0.25) as compared with control subjects (2.44+/-0.33; p<0.0001 for both groups). The PCr/ATP did not correlate with LV ejection fraction or mass index.Altered expression of dystrophin leads to a reduction in the PCr/ATP. Since this reduction did not correlate with indexes of left ventricular function, this raises the possibility of a direct link between altered dystrophin expression and the development of cardiomyopathy in such patients." @default.
• W2023593630 created "2016-06-24" @default.
• W2023593630 creator A5011269908 @default.
• W2023593630 creator A5031640268 @default.
• W2023593630 creator A5032891489 @default.
• W2023593630 creator A5037350616 @default.
• W2023593630 creator A5042239138 @default.
• W2023593630 creator A5080625220 @default.
• W2023593630 creator A5082915677 @default.
• W2023593630 creator A5089234882 @default.
• W2023593630 date "2000-11-01" @default.
• W2023593630 modified "2023-10-05" @default.
• W2023593630 title "Magnetic resonance spectroscopy evidence of abnormal cardiac energetics in Xp21 muscular dystrophy" @default.
• W2023593630 cites W1849159432 @default.
• W2023593630 cites W1971317490 @default.
• W2023593630 cites W1974248631 @default.
• W2023593630 cites W1974395224 @default.
• W2023593630 cites W1977052313 @default.
• W2023593630 cites W1990265468 @default.
• W2023593630 cites W1992141724 @default.
• W2023593630 cites W1994197068 @default.
• W2023593630 cites W2011181628 @default.
• W2023593630 cites W2016431737 @default.
• W2023593630 cites W2017839586 @default.
• W2023593630 cites W2017940848 @default.
• W2023593630 cites W2031789342 @default.
• W2023593630 cites W2036379925 @default.
• W2023593630 cites W2036637373 @default.
• W2023593630 cites W2037361270 @default.
• W2023593630 cites W2053048384 @default.
• W2023593630 cites W2054111304 @default.
• W2023593630 cites W2064374012 @default.
• W2023593630 cites W2077283792 @default.
• W2023593630 cites W2078711762 @default.
• W2023593630 cites W2081133653 @default.
• W2023593630 cites W2086619682 @default.
• W2023593630 cites W2093800259 @default.
• W2023593630 cites W2132627057 @default.
• W2023593630 cites W2141759547 @default.
• W2023593630 cites W2150871104 @default.
• W2023593630 cites W2151501906 @default.
• W2023593630 cites W2153985164 @default.
• W2023593630 cites W2161233221 @default.
• W2023593630 cites W2170832171 @default.
• W2023593630 cites W2172041803 @default.
• W2023593630 cites W2327700938 @default.
• W2023593630 cites W42574947 @default.
• W2023593630 doi "https://doi.org/10.1016/s0735-1097(00)00960-8" @default.
• W2023593630 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11092670" @default.
• W2023593630 hasPublicationYear "2000" @default.
• W2023593630 type Work @default.
• W2023593630 sameAs 2023593630 @default.
• W2023593630 citedByCount "50" @default.
• W2023593630 countsByYear W20235936302013 @default.
• W2023593630 countsByYear W20235936302014 @default.
• W2023593630 countsByYear W20235936302015 @default.
• W2023593630 countsByYear W20235936302016 @default.
• W2023593630 countsByYear W20235936302017 @default.
• W2023593630 countsByYear W20235936302018 @default.
• W2023593630 countsByYear W20235936302019 @default.
• W2023593630 countsByYear W20235936302020 @default.
• W2023593630 countsByYear W20235936302022 @default.
• W2023593630 crossrefType "journal-article" @default.
• W2023593630 hasAuthorship W2023593630A5011269908 @default.
• W2023593630 hasAuthorship W2023593630A5031640268 @default.
• W2023593630 hasAuthorship W2023593630A5032891489 @default.
• W2023593630 hasAuthorship W2023593630A5037350616 @default.
• W2023593630 hasAuthorship W2023593630A5042239138 @default.
• W2023593630 hasAuthorship W2023593630A5080625220 @default.
• W2023593630 hasAuthorship W2023593630A5082915677 @default.
• W2023593630 hasAuthorship W2023593630A5089234882 @default.
• W2023593630 hasBestOaLocation W20235936301 @default.
• W2023593630 hasConcept C111566952 @default.
• W2023593630 hasConcept C126322002 @default.
• W2023593630 hasConcept C134018914 @default.
• W2023593630 hasConcept C164705383 @default.
• W2023593630 hasConcept C2778198053 @default.
• W2023593630 hasConcept C2778626300 @default.
• W2023593630 hasConcept C2778797674 @default.
• W2023593630 hasConcept C2778943923 @default.
• W2023593630 hasConcept C2778996579 @default.
• W2023593630 hasConcept C2779030066 @default.
• W2023593630 hasConcept C2779564974 @default.
• W2023593630 hasConcept C2779959927 @default.
• W2023593630 hasConcept C2780394045 @default.
• W2023593630 hasConcept C2986317502 @default.
• W2023593630 hasConcept C71924100 @default.
• W2023593630 hasConcept C78085059 @default.
• W2023593630 hasConceptScore W2023593630C111566952 @default.
• W2023593630 hasConceptScore W2023593630C126322002 @default.
• W2023593630 hasConceptScore W2023593630C134018914 @default.
• W2023593630 hasConceptScore W2023593630C164705383 @default.
• W2023593630 hasConceptScore W2023593630C2778198053 @default.
• W2023593630 hasConceptScore W2023593630C2778626300 @default.
• W2023593630 hasConceptScore W2023593630C2778797674 @default.
• W2023593630 hasConceptScore W2023593630C2778943923 @default.
• W2023593630 hasConceptScore W2023593630C2778996579 @default.
• W2023593630 hasConceptScore W2023593630C2779030066 @default.

• next