FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023596297> ?p ?o ?g. }

• W2023596297 endingPage "650" @default.
• W2023596297 startingPage "644" @default.
• W2023596297 abstract "Angiogenesis plays a pivotal role in many processes. Here, we studied whether angiogenesis to basic fibroblast growth factor (bFGF) in normal and portal hypertensive rats requires nitric oxide (NO).To measure angiogenesis in vivo, two Teflon rings filled with collagen I (Vitrogen 100) were fixed in the mesenteric cavity at day 0, with one supplemented with bFGF (100 ng). Portal hypertension was induced by partial portal vein ligation (PVL). Sham-operated rats served as controls (CON). The role of NO was tested by adding the NO formation antagonist N(omega)-nitro-L-arginine (NNA; 3.3 mg/kg per day) to the drinking water. After 16 days, rings were explanted and embedded, and vessels were morphometrically counted.bFGF significantly stimulated vessel formation per implant in CON rats (from 624 +/- 97 without stimulation to 1123 +/- 171, n = 11, P < 0.01), but not in PVL rats (from 1106 +/- 174 without stimulation to 1046 +/- 202, n = 9). Without stimulation, numbers of ingrown vessels were significantly (P < 0.05) higher in PVL compared to CON rats. NNA substantially inhibited angiogenesis in both groups (P < 0.01). Vessel numbers were 202 +/- 124 for PVL (n = 5) and 197 +/- 14 for CON (n = 5) animals. bFGF did not reverse angiogenesis prevented by NNA (373 +/- 98 for PVL, 265 +/- 26 for CON, n = 5 per group, NS).NO formation inhibition diminishes both unstimulated and bFGF-stimulated angiogenesis in CON rats. Moreover, bFGF cannot rescue NNA-inhibited angiogenesis in PVL rats." @default.
• W2023596297 created "2016-06-24" @default.
• W2023596297 creator A5008496277 @default.
• W2023596297 creator A5010093671 @default.
• W2023596297 creator A5033055304 @default.
• W2023596297 creator A5083079315 @default.
• W2023596297 creator A5083137596 @default.
• W2023596297 date "2001-05-01" @default.
• W2023596297 modified "2023-10-16" @default.
• W2023596297 title "In vivo angiogenesis in normal and portal hypertensive rats: role of basic fibroblast growth factor and nitric oxide" @default.
• W2023596297 cites W1575024810 @default.
• W2023596297 cites W1679229092 @default.
• W2023596297 cites W1968861450 @default.
• W2023596297 cites W1974332277 @default.
• W2023596297 cites W1991045646 @default.
• W2023596297 cites W2009029293 @default.
• W2023596297 cites W2010812148 @default.
• W2023596297 cites W2015447656 @default.
• W2023596297 cites W2015521743 @default.
• W2023596297 cites W2041034845 @default.
• W2023596297 cites W2042397185 @default.
• W2023596297 cites W2049517700 @default.
• W2023596297 cites W2056148198 @default.
• W2023596297 cites W2058934794 @default.
• W2023596297 cites W2063022757 @default.
• W2023596297 cites W2072527651 @default.
• W2023596297 cites W2077571136 @default.
• W2023596297 cites W2086719224 @default.
• W2023596297 cites W2086757889 @default.
• W2023596297 cites W2095967648 @default.
• W2023596297 cites W2118148454 @default.
• W2023596297 cites W2130870274 @default.
• W2023596297 cites W2137061681 @default.
• W2023596297 cites W2143260418 @default.
• W2023596297 cites W2146564676 @default.
• W2023596297 cites W2151967532 @default.
• W2023596297 cites W2154041115 @default.
• W2023596297 cites W2160997491 @default.
• W2023596297 cites W2168981489 @default.
• W2023596297 cites W2171023162 @default.
• W2023596297 cites W2171864934 @default.
• W2023596297 cites W4245635197 @default.
• W2023596297 doi "https://doi.org/10.1016/s0168-8278(00)00064-7" @default.
• W2023596297 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11434609" @default.
• W2023596297 hasPublicationYear "2001" @default.
• W2023596297 type Work @default.
• W2023596297 sameAs 2023596297 @default.
• W2023596297 citedByCount "69" @default.
• W2023596297 countsByYear W20235962972012 @default.
• W2023596297 countsByYear W20235962972013 @default.
• W2023596297 countsByYear W20235962972014 @default.
• W2023596297 countsByYear W20235962972015 @default.
• W2023596297 countsByYear W20235962972016 @default.
• W2023596297 countsByYear W20235962972017 @default.
• W2023596297 countsByYear W20235962972018 @default.
• W2023596297 countsByYear W20235962972019 @default.
• W2023596297 countsByYear W20235962972020 @default.
• W2023596297 countsByYear W20235962972021 @default.
• W2023596297 countsByYear W20235962972022 @default.
• W2023596297 crossrefType "journal-article" @default.
• W2023596297 hasAuthorship W2023596297A5008496277 @default.
• W2023596297 hasAuthorship W2023596297A5010093671 @default.
• W2023596297 hasAuthorship W2023596297A5033055304 @default.
• W2023596297 hasAuthorship W2023596297A5083079315 @default.
• W2023596297 hasAuthorship W2023596297A5083137596 @default.
• W2023596297 hasConcept C126322002 @default.
• W2023596297 hasConcept C134018914 @default.
• W2023596297 hasConcept C150903083 @default.
• W2023596297 hasConcept C167734588 @default.
• W2023596297 hasConcept C170493617 @default.
• W2023596297 hasConcept C207001950 @default.
• W2023596297 hasConcept C24998067 @default.
• W2023596297 hasConcept C2775960820 @default.
• W2023596297 hasConcept C2777025900 @default.
• W2023596297 hasConcept C2777214474 @default.
• W2023596297 hasConcept C2777587049 @default.
• W2023596297 hasConcept C2778271429 @default.
• W2023596297 hasConcept C2778808290 @default.
• W2023596297 hasConcept C2780394083 @default.
• W2023596297 hasConcept C519581460 @default.
• W2023596297 hasConcept C71924100 @default.
• W2023596297 hasConcept C86803240 @default.
• W2023596297 hasConceptScore W2023596297C126322002 @default.
• W2023596297 hasConceptScore W2023596297C134018914 @default.
• W2023596297 hasConceptScore W2023596297C150903083 @default.
• W2023596297 hasConceptScore W2023596297C167734588 @default.
• W2023596297 hasConceptScore W2023596297C170493617 @default.
• W2023596297 hasConceptScore W2023596297C207001950 @default.
• W2023596297 hasConceptScore W2023596297C24998067 @default.
• W2023596297 hasConceptScore W2023596297C2775960820 @default.
• W2023596297 hasConceptScore W2023596297C2777025900 @default.
• W2023596297 hasConceptScore W2023596297C2777214474 @default.
• W2023596297 hasConceptScore W2023596297C2777587049 @default.
• W2023596297 hasConceptScore W2023596297C2778271429 @default.
• W2023596297 hasConceptScore W2023596297C2778808290 @default.
• W2023596297 hasConceptScore W2023596297C2780394083 @default.
• W2023596297 hasConceptScore W2023596297C519581460 @default.
• W2023596297 hasConceptScore W2023596297C71924100 @default.

• next