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• W2023604693 abstract "The present study investigates the hepatoprotective activity of Myrica rubra Sieb. et Zucc. extract (MCE) against acetaminophen (AAP)-induced liver damage and elucidates the possible mechanisms behind the hepatoprotection observed. Serum alanine aminotransferase and serum aspartate aminotransferase activities were detected and liver histopathology was observed. Mitochondrial swelling, mitochondrial membrane potential, and voltage-dependent anion channel (VDAC) gene transcription were also investigated. The results showed that 50, 150, and 450 mg/kg MCE could restore AAP-induced changes in mice liver in a dose-dependent manner. The mechanisms behind the hepatoprotective effects of MCE may be related to the mitochondrial protection of liver cells, especially of VDAC, an important protein on the outer membrane of the mitochondria." @default.
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• W2023604693 date "2013-01-01" @default.
• W2023604693 modified "2023-09-29" @default.
• W2023604693 title "Mitochondrial Protective Effects of Myrica rubra Extract Against Acetaminophen-Induced Toxicity" @default.
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• W2023604693 doi "https://doi.org/10.1142/s0192415x13500717" @default.
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