FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023606475> ?p ?o ?g. }

• W2023606475 endingPage "168" @default.
• W2023606475 startingPage "162" @default.
• W2023606475 abstract "alpha-fetoprotein (AFP), human chorionic gonadotropin (HCG), and lactate dehydrogenase (LDH) closely follow the course of germ cell tumors (GCTs) and are widely used for diagnosis, prognosis, and follow-up purposes. The objective of this study was to assess the concordance of tumor markers at the time of diagnosis and recurrence.The authors reviewed the records of 794 patients with GCTs treated in three Spanish hospitals from 1977-1996 and analyzed the concordance between AFP, HCG, and LDH levels at diagnosis and first and second recurrence. A positive marker was defined as a level of AFP > 10 ng/mL, HCG > 5 IU/L, or LDH > the upper limit of normal. One hundred twenty-five patients were identified who developed a first recurrence (123 had marker levels recorded). The median age was 27 years (range, 14-78 years). Histology was seminoma in 36 patients (29%) and nonseminomatous GCT (NSGCT) in 87 patients (71%).Seventy-nine patients (64%) had elevated tumor markers at diagnosis and 76 (62%) at first recurrence. An elevated marker was present at first recurrence in 58 of 79 patients (73%) with initially positive markers and in 18 of 44 patients (41%) with initially negative markers. In 84 of 123 patients (68%), the same marker pattern (positive or negative) was present at the time of diagnosis and at first recurrence, 78% in seminomas and 64% in NSGCTs. The earliest indicator of recurrence was an elevated marker in patients with NSGCTs and a radiologic finding in patients with seminomas. Thirty patients developed a second recurrence, 27 of whom (90%) had the same marker pattern as at first recurrence.Tumor marker pattern at diagnosis is not a good predictor of the pattern at recurrence, particularly in patients with NSGCTs. Marker assessment should be included in the follow-up schedule regardless of levels at the time of diagnosis. Early detection of recurrence should not rely only on marker levels, even in patients with elevated levels at presentation." @default.
• W2023606475 created "2016-06-24" @default.
• W2023606475 creator A5016929192 @default.
• W2023606475 creator A5033987639 @default.
• W2023606475 creator A5035175323 @default.
• W2023606475 creator A5041861170 @default.
• W2023606475 creator A5042192155 @default.
• W2023606475 creator A5052765751 @default.
• W2023606475 creator A5053895349 @default.
• W2023606475 creator A5056091871 @default.
• W2023606475 creator A5064181874 @default.
• W2023606475 creator A5075424068 @default.
• W2023606475 date "2000-01-01" @default.
• W2023606475 modified "2023-10-18" @default.
• W2023606475 title "Tumor markers at the time of recurrence in patients with germ cell tumors" @default.
• W2023606475 cites W108407778 @default.
• W2023606475 cites W140750605 @default.
• W2023606475 cites W1483097106 @default.
• W2023606475 cites W172019600 @default.
• W2023606475 cites W1861752925 @default.
• W2023606475 cites W1989052970 @default.
• W2023606475 cites W1990930370 @default.
• W2023606475 cites W2021825110 @default.
• W2023606475 cites W2024391689 @default.
• W2023606475 cites W2030235235 @default.
• W2023606475 cites W2035813847 @default.
• W2023606475 cites W2067674360 @default.
• W2023606475 cites W2078983003 @default.
• W2023606475 cites W2083105900 @default.
• W2023606475 cites W2093126448 @default.
• W2023606475 cites W2187668060 @default.
• W2023606475 cites W2226054732 @default.
• W2023606475 cites W2282394251 @default.
• W2023606475 cites W2472648617 @default.
• W2023606475 cites W4249486644 @default.
• W2023606475 cites W4293241248 @default.
• W2023606475 cites W44254208 @default.
• W2023606475 doi "https://doi.org/10.1002/(sici)1097-0142(20000101)88:1<162::aid-cncr22>3.0.co;2-v" @default.
• W2023606475 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10618619" @default.
• W2023606475 hasPublicationYear "2000" @default.
• W2023606475 type Work @default.
• W2023606475 sameAs 2023606475 @default.
• W2023606475 citedByCount "63" @default.
• W2023606475 countsByYear W20236064752012 @default.
• W2023606475 countsByYear W20236064752013 @default.
• W2023606475 countsByYear W20236064752014 @default.
• W2023606475 countsByYear W20236064752015 @default.
• W2023606475 countsByYear W20236064752016 @default.
• W2023606475 countsByYear W20236064752018 @default.
• W2023606475 countsByYear W20236064752019 @default.
• W2023606475 countsByYear W20236064752020 @default.
• W2023606475 countsByYear W20236064752021 @default.
• W2023606475 countsByYear W20236064752022 @default.
• W2023606475 countsByYear W20236064752023 @default.
• W2023606475 crossrefType "journal-article" @default.
• W2023606475 hasAuthorship W2023606475A5016929192 @default.
• W2023606475 hasAuthorship W2023606475A5033987639 @default.
• W2023606475 hasAuthorship W2023606475A5035175323 @default.
• W2023606475 hasAuthorship W2023606475A5041861170 @default.
• W2023606475 hasAuthorship W2023606475A5042192155 @default.
• W2023606475 hasAuthorship W2023606475A5052765751 @default.
• W2023606475 hasAuthorship W2023606475A5053895349 @default.
• W2023606475 hasAuthorship W2023606475A5056091871 @default.
• W2023606475 hasAuthorship W2023606475A5064181874 @default.
• W2023606475 hasAuthorship W2023606475A5075424068 @default.
• W2023606475 hasConcept C104317684 @default.
• W2023606475 hasConcept C121608353 @default.
• W2023606475 hasConcept C126322002 @default.
• W2023606475 hasConcept C142724271 @default.
• W2023606475 hasConcept C160798450 @default.
• W2023606475 hasConcept C2775948956 @default.
• W2023606475 hasConcept C2776694085 @default.
• W2023606475 hasConcept C2776938808 @default.
• W2023606475 hasConcept C2778019345 @default.
• W2023606475 hasConcept C2778074268 @default.
• W2023606475 hasConcept C2779122487 @default.
• W2023606475 hasConcept C2780521871 @default.
• W2023606475 hasConcept C2780624289 @default.
• W2023606475 hasConcept C2781447364 @default.
• W2023606475 hasConcept C55493867 @default.
• W2023606475 hasConcept C57742111 @default.
• W2023606475 hasConcept C71315377 @default.
• W2023606475 hasConcept C71924100 @default.
• W2023606475 hasConcept C86803240 @default.
• W2023606475 hasConcept C90924648 @default.
• W2023606475 hasConceptScore W2023606475C104317684 @default.
• W2023606475 hasConceptScore W2023606475C121608353 @default.
• W2023606475 hasConceptScore W2023606475C126322002 @default.
• W2023606475 hasConceptScore W2023606475C142724271 @default.
• W2023606475 hasConceptScore W2023606475C160798450 @default.
• W2023606475 hasConceptScore W2023606475C2775948956 @default.
• W2023606475 hasConceptScore W2023606475C2776694085 @default.
• W2023606475 hasConceptScore W2023606475C2776938808 @default.
• W2023606475 hasConceptScore W2023606475C2778019345 @default.
• W2023606475 hasConceptScore W2023606475C2778074268 @default.
• W2023606475 hasConceptScore W2023606475C2779122487 @default.
• W2023606475 hasConceptScore W2023606475C2780521871 @default.
• W2023606475 hasConceptScore W2023606475C2780624289 @default.

• next