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- W2023606718 endingPage "831" @default.
- W2023606718 startingPage "823" @default.
- W2023606718 abstract "Within the last decade, several peptides have been discovered on the basis of their ability to inhibit the growth of potential microbial pathogens. These so-called antimicrobial peptides participate in the innate immune response by providing a rapid first-line defense against infection. Recent advances in this field have shown that peptides belonging to the cathelicidin and defensin gene families are of particular importance to the mammalian immune defense system. This review discusses the biology of these molecules, with emphasis on their structure, processing, expression and function. Current evidence has shown that both cathelicidins and defensins are multifunctional and that they act both as natural antibiotics and as signaling molecules that activate host cell processes involved in immune defense and repair. The abnormal expression of these peptides has also been associated with human disease. Current and future studies are likely to implicate the presence of antimicrobial peptides in several unexplained human inflammatory disorders and to provide novel therapeutic approaches to the treatment of disease. (J Allergy Clin Immunol 2002;110:823-31.)" @default.
- W2023606718 created "2016-06-24" @default.
- W2023606718 creator A5055585390 @default.
- W2023606718 creator A5064797671 @default.
- W2023606718 creator A5088138527 @default.
- W2023606718 creator A5089950279 @default.
- W2023606718 date "2002-12-01" @default.
- W2023606718 modified "2023-10-18" @default.
- W2023606718 title "Biology and clinical relevance of naturally occurring antimicrobial peptides" @default.
- W2023606718 cites W126340564 @default.
- W2023606718 cites W1481684176 @default.
- W2023606718 cites W1488482313 @default.
- W2023606718 cites W1500925296 @default.
- W2023606718 cites W1506297407 @default.
- W2023606718 cites W1531531679 @default.
- W2023606718 cites W1571292455 @default.
- W2023606718 cites W1600197356 @default.
- W2023606718 cites W1608815389 @default.
- W2023606718 cites W1761222131 @default.
- W2023606718 cites W1896164923 @default.
- W2023606718 cites W1951818427 @default.
- W2023606718 cites W1964758221 @default.
- W2023606718 cites W1965135642 @default.
- W2023606718 cites W1968898932 @default.
- W2023606718 cites W1970537989 @default.
- W2023606718 cites W1975904765 @default.
- W2023606718 cites W1984706012 @default.
- W2023606718 cites W1986224819 @default.
- W2023606718 cites W1987159173 @default.
- W2023606718 cites W1991625690 @default.
- W2023606718 cites W1993355081 @default.
- W2023606718 cites W2002193923 @default.
- W2023606718 cites W2003738186 @default.
- W2023606718 cites W2010762616 @default.
- W2023606718 cites W2012845796 @default.
- W2023606718 cites W2015566739 @default.
- W2023606718 cites W2021030655 @default.
- W2023606718 cites W2021413161 @default.
- W2023606718 cites W2022283846 @default.
- W2023606718 cites W2025063713 @default.
- W2023606718 cites W2025816092 @default.
- W2023606718 cites W2027074022 @default.
- W2023606718 cites W2029331076 @default.
- W2023606718 cites W2029727629 @default.
- W2023606718 cites W2030041616 @default.
- W2023606718 cites W2034280103 @default.
- W2023606718 cites W2037701623 @default.
- W2023606718 cites W2042350961 @default.
- W2023606718 cites W2050242176 @default.
- W2023606718 cites W2051142131 @default.
- W2023606718 cites W2053044114 @default.
- W2023606718 cites W2059361679 @default.
- W2023606718 cites W2060300255 @default.
- W2023606718 cites W2065273951 @default.
- W2023606718 cites W2069492069 @default.
- W2023606718 cites W2069813732 @default.
- W2023606718 cites W2072771934 @default.
- W2023606718 cites W2072841683 @default.
- W2023606718 cites W2073865475 @default.
- W2023606718 cites W2076916880 @default.
- W2023606718 cites W2077560507 @default.
- W2023606718 cites W2085793178 @default.
- W2023606718 cites W2090042814 @default.
- W2023606718 cites W2090407536 @default.
- W2023606718 cites W2091604858 @default.
- W2023606718 cites W2094036101 @default.
- W2023606718 cites W2097098774 @default.
- W2023606718 cites W2099107614 @default.
- W2023606718 cites W2104159258 @default.
- W2023606718 cites W2116114158 @default.
- W2023606718 cites W2116558722 @default.
- W2023606718 cites W2116697371 @default.
- W2023606718 cites W2119123809 @default.
- W2023606718 cites W2124508823 @default.
- W2023606718 cites W2125293812 @default.
- W2023606718 cites W2126466156 @default.
- W2023606718 cites W2127449370 @default.
- W2023606718 cites W2130612498 @default.
- W2023606718 cites W2134582553 @default.
- W2023606718 cites W2134912543 @default.
- W2023606718 cites W2136261162 @default.
- W2023606718 cites W2139212892 @default.
- W2023606718 cites W2140151651 @default.
- W2023606718 cites W2140472579 @default.
- W2023606718 cites W2141676495 @default.
- W2023606718 cites W2144219110 @default.
- W2023606718 cites W2148067829 @default.
- W2023606718 cites W2156173084 @default.
- W2023606718 cites W2157252835 @default.
- W2023606718 cites W2157705461 @default.
- W2023606718 cites W2158113024 @default.
- W2023606718 cites W2161998284 @default.
- W2023606718 cites W2163208720 @default.
- W2023606718 cites W2166791780 @default.
- W2023606718 cites W2167925233 @default.
- W2023606718 cites W2168400885 @default.
- W2023606718 cites W2169759699 @default.
- W2023606718 cites W2182160369 @default.