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• W2023609635 abstract "Annals of the New York Academy of SciencesVolume 284, Issue 1 p. 9-20 INHIBITION OF ADENOSINE DEAMINASE BY CO-VIDARABINE AND ITS EFFECT ON THE METABOLIC DISPOSITION OF ADENINE ARABINOSIDE (VIDARABINE) P. E. Borondy, P. E. Borondy Research Laboratories Parke, Davis & Company Ann Arbor, Michigan 48106Search for more papers by this authorT. Chang, T. Chang Research Laboratories Parke, Davis & Company Ann Arbor, Michigan 48106Search for more papers by this authorE. Maschewske, E. Maschewske Research Laboratories Parke, Davis & Company Ann Arbor, Michigan 48106Search for more papers by this authorA. J. Glazko, A. J. Glazko Research Laboratories Parke, Davis & Company Ann Arbor, Michigan 48106Search for more papers by this author P. E. Borondy, P. E. Borondy Research Laboratories Parke, Davis & Company Ann Arbor, Michigan 48106Search for more papers by this authorT. Chang, T. Chang Research Laboratories Parke, Davis & Company Ann Arbor, Michigan 48106Search for more papers by this authorE. Maschewske, E. Maschewske Research Laboratories Parke, Davis & Company Ann Arbor, Michigan 48106Search for more papers by this authorA. J. Glazko, A. J. Glazko Research Laboratories Parke, Davis & Company Ann Arbor, Michigan 48106Search for more papers by this author First published: May 1977 https://doi.org/10.1111/j.1749-6632.1977.tb21932.xCitations: 28AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Nhda, T., T. Tsuruoka, N. Ezaki, T. Shomura & H. Umezawa. 1967. Isolation and characterization of coformycin. 153rd Scientific Meeting, Japan Antibiotics Research Assoc., Tokyo, Jan. 27. 2 Sawa, T., Y. Fukagawa, I. Homma, T. Takeuchi & H. Umezawa. 1967. Mode of inhibition of coformycin on adenosinedeaminase. J. Antibiot. (Japan) Ser. A 20: 227–231. 3 Woo, P. W. K., H. W. Dion, S. M. Lange, L. F. Dahl & L. J. Durham. 1974. A novel adenosine and ara-A deaminase inhibitor, (R)-3-(2-deoxy-β-D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol. J. Heterocyc. Chem. 11: 641–643. 4 Nakamura, H., G. Koyoma, Y. Litaka, M. Ohno, N. Yagisawa, S. Kondo, K. Maeda & H. Umezawa. 1974. Structure of coformycin, an unusual nucleoside of microbial origin. J. Amer. Chem. Soc. 96: 4326–4327. 5 Schaeffer, H. J., & C. F. Schwender. 1974. Enzyme inhibitors. 26. Bridging hydrophobic and hydrophilic regions on adenosine deaminase with some 9-(2-hydroxy-3-alkyl) adenines. J. Med. Chem. 17: 6–8. 6 Bryson, Y., J. D. Connor, L. Sweetman, S. Carey, M. A. Stuckey & R. Buchanan. 1974. Determination of plaque inhibitory activity of adenine arabinoside (9-β-D-arabinosyladenine) for herpesviruses using an adenosine deaminase inhibitor. Antimicrob. Agents Chemother. 6: 98–101. 7 Connor, L., L. Sweetman, S. Carey, M. A. Stuckey & R. A. Buchanan. 1974. Effect of adenosine deaminase upon the antiviral activity in vitro of adenine arabinoside for vaccinia virus. Antimicrob. Agents Chemother. 6: 630–636. 8 Ch'ien, L. T., N. J. Cannon, L. J. Charamella, W. E. Dismukes, R. J. Whitley, R. A. Buchanan & C. A. Alford, Jr. 1973. Effect of adenine arabinoside on severe Herpesvirus hominis infections in man. J. Infect. Dis. 128: 658–663. 9 Bodey, G. P., J. Gottlieb, K. B. McCrediem & E. J. Freireich. 1974. Arabinosyl adenine (ara-A) as an antitumor agent. Proc. Amer. Assoc. Cancer Res. 15: 514 (abstr.). 10 Brink, J. J. & G. A. Le Page. 1964. Metabolism and distribution of 9-β-Darabinosyladenine in mouse tissues. Cancer Res. 24: 1042–1049. 11 Miller, F. A., G. J. Dixon, J. Ehrlich, B. J. Sloan & I. W. McLean, Jr. 1969. Antiviral activity of 9-β-D-arabinofuranosyladenine. I. Cell culture studies. Antimicrob. Agents Chemother. (Amer. Soc. Microbiol., Washington, D.C.) 1968: 136–147. 12 Lineweaver, H. & D. Burk. 1934. The determination of enzyme dissociation constants. J. Amer. Chem. Soc. 56: 658–666. 13 Gonzales, L. W. & S. E. Geel. 1975. TLC of brain adenine nucleosides and nucleotides and determination of ATP specific activity. Anal. Biochem. 63: 400–413. 14 Schwartz, P. M. & J. C. Drach. 1975. Separation of arabinosyl, ribosyl, and deoxyribosyl purine nucleotides by thin-layer chromatography. J. Chromatoaraphy 106: 200–203. 15 Chang, T., E. Maschewske, L. Croskey, H. Schneider & A. J. Glazko. 1975. Effect of a new adenosine deaminase inhibitor (co-vidarabine; Co-V) on the plasma levels and urinary excretion of arabionsyladenine (vidarabine; ara-A). 15th Intersci. Conf. on Antimicrob. Agents & Chemother., Washington D.C. , Sept. 24–26. 16 Glazko, A. J., T. Chang, J. C. Drach, D. R. Mourer, P. E. Borondy, H. Schneider. L. Croskey & E. Maschewske. 1975. Species differences in the metabolic disposition of ara-A. In Adenine Arabinoside: An Antiviral Agent. D. Pavan-Langston, R. A. Buchanan & C. A. Alford, Eds. Raven Press, New York . 17 Chang, T. & A. J. Glazko. 1976. Effect of an adenosine deaminase inhibitor on the uptake and metabolism of arabinosyl adenine (vidarabine) by intact human erythrocytes. Res. Commun. Chem. Pathol. Pharmacol. 14: 127–140. Citing Literature Volume284, Issue1Third Conference on Antiviral SubstancesMay 1977Pages 9-20 ReferencesRelatedInformation" @default.
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