Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023609840> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2023609840 endingPage "131" @default.
- W2023609840 startingPage "115" @default.
- W2023609840 abstract "Currents flowing through the postsynaptic membrane of an active synapse will tend to change the concentrations of ions in the synaptic cleft. Published experimental data are used to predict (a) the sodium and potassium concentration changes in the cleft at the frog neuromuscular junction, and (b) the sodium depletion in the cleft under a Ia synaptic bouton on a cat motoneuron. Significant concentration changes are predicted at both synapses. These changes will contribute to the time dependence of the observed current and will cause the reversal potential of the current to be time dependent. At the frog neuromuscular junction, the time course of the endplate current has been shown previously to depend on the magnitude of the current flowing (at a given potential). We attribute this to changes of the cleft ion concentration. The time dependent changes of the endplate current reversal potential that we predict for the neuromuscular junction are probably too small to be detected. This is because the effects of sodium depletion and potassium accumulation on the reversal potential almost cancel. We predict that near the reversal potential small currents of complex time course will remain, i.e. no true reversl potential exists. Such currents have previously been experimentally. At the cat Ia synapse, the synaptic current is predicted to deplete a significant fraction of the available extracellular sodium ions. Consequently, the magnitude of the synaptic current should be relatively independent of the number of postsynaptic channels activated, and of the membrane potental, as has previously been found experimentally." @default.
- W2023609840 created "2016-06-24" @default.
- W2023609840 creator A5047965342 @default.
- W2023609840 creator A5054589692 @default.
- W2023609840 date "1979-11-30" @default.
- W2023609840 modified "2023-09-25" @default.
- W2023609840 title "Synaptic transmission : ion concentration changes in the synaptic cleft" @default.
- W2023609840 cites W2018662775 @default.
- W2023609840 cites W2026616254 @default.
- W2023609840 cites W2030080809 @default.
- W2023609840 cites W2074476623 @default.
- W2023609840 cites W2083239247 @default.
- W2023609840 cites W2144604336 @default.
- W2023609840 cites W2159886846 @default.
- W2023609840 cites W2341541642 @default.
- W2023609840 cites W2437811765 @default.
- W2023609840 cites W2474589103 @default.
- W2023609840 cites W4210635511 @default.
- W2023609840 cites W50222339 @default.
- W2023609840 doi "https://doi.org/10.1098/rspb.1979.0095" @default.
- W2023609840 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/42066" @default.
- W2023609840 hasPublicationYear "1979" @default.
- W2023609840 type Work @default.
- W2023609840 sameAs 2023609840 @default.
- W2023609840 citedByCount "21" @default.
- W2023609840 countsByYear W20236098402016 @default.
- W2023609840 countsByYear W20236098402023 @default.
- W2023609840 crossrefType "journal-article" @default.
- W2023609840 hasAuthorship W2023609840A5047965342 @default.
- W2023609840 hasAuthorship W2023609840A5054589692 @default.
- W2023609840 hasConcept C121332964 @default.
- W2023609840 hasConcept C12554922 @default.
- W2023609840 hasConcept C127445978 @default.
- W2023609840 hasConcept C134018914 @default.
- W2023609840 hasConcept C147944092 @default.
- W2023609840 hasConcept C148043351 @default.
- W2023609840 hasConcept C169760540 @default.
- W2023609840 hasConcept C170493617 @default.
- W2023609840 hasConcept C178790620 @default.
- W2023609840 hasConcept C179053475 @default.
- W2023609840 hasConcept C181911157 @default.
- W2023609840 hasConcept C185263204 @default.
- W2023609840 hasConcept C185592680 @default.
- W2023609840 hasConcept C197341189 @default.
- W2023609840 hasConcept C200170125 @default.
- W2023609840 hasConcept C2777240379 @default.
- W2023609840 hasConcept C2778071365 @default.
- W2023609840 hasConcept C2993285035 @default.
- W2023609840 hasConcept C3020341438 @default.
- W2023609840 hasConcept C50952357 @default.
- W2023609840 hasConcept C537181965 @default.
- W2023609840 hasConcept C55493867 @default.
- W2023609840 hasConcept C86803240 @default.
- W2023609840 hasConcept C97355855 @default.
- W2023609840 hasConceptScore W2023609840C121332964 @default.
- W2023609840 hasConceptScore W2023609840C12554922 @default.
- W2023609840 hasConceptScore W2023609840C127445978 @default.
- W2023609840 hasConceptScore W2023609840C134018914 @default.
- W2023609840 hasConceptScore W2023609840C147944092 @default.
- W2023609840 hasConceptScore W2023609840C148043351 @default.
- W2023609840 hasConceptScore W2023609840C169760540 @default.
- W2023609840 hasConceptScore W2023609840C170493617 @default.
- W2023609840 hasConceptScore W2023609840C178790620 @default.
- W2023609840 hasConceptScore W2023609840C179053475 @default.
- W2023609840 hasConceptScore W2023609840C181911157 @default.
- W2023609840 hasConceptScore W2023609840C185263204 @default.
- W2023609840 hasConceptScore W2023609840C185592680 @default.
- W2023609840 hasConceptScore W2023609840C197341189 @default.
- W2023609840 hasConceptScore W2023609840C200170125 @default.
- W2023609840 hasConceptScore W2023609840C2777240379 @default.
- W2023609840 hasConceptScore W2023609840C2778071365 @default.
- W2023609840 hasConceptScore W2023609840C2993285035 @default.
- W2023609840 hasConceptScore W2023609840C3020341438 @default.
- W2023609840 hasConceptScore W2023609840C50952357 @default.
- W2023609840 hasConceptScore W2023609840C537181965 @default.
- W2023609840 hasConceptScore W2023609840C55493867 @default.
- W2023609840 hasConceptScore W2023609840C86803240 @default.
- W2023609840 hasConceptScore W2023609840C97355855 @default.
- W2023609840 hasIssue "1162" @default.
- W2023609840 hasLocation W20236098401 @default.
- W2023609840 hasLocation W20236098402 @default.
- W2023609840 hasOpenAccess W2023609840 @default.
- W2023609840 hasPrimaryLocation W20236098401 @default.
- W2023609840 hasRelatedWork W1487690923 @default.
- W2023609840 hasRelatedWork W1966727055 @default.
- W2023609840 hasRelatedWork W1979165195 @default.
- W2023609840 hasRelatedWork W1996009665 @default.
- W2023609840 hasRelatedWork W2004552717 @default.
- W2023609840 hasRelatedWork W2013274902 @default.
- W2023609840 hasRelatedWork W2023609840 @default.
- W2023609840 hasRelatedWork W2250780996 @default.
- W2023609840 hasRelatedWork W3158756789 @default.
- W2023609840 hasRelatedWork W4384926679 @default.
- W2023609840 hasVolume "206" @default.
- W2023609840 isParatext "false" @default.
- W2023609840 isRetracted "false" @default.
- W2023609840 magId "2023609840" @default.
- W2023609840 workType "article" @default.