FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023609911> ?p ?o ?g. }

• W2023609911 endingPage "1282" @default.
• W2023609911 startingPage "1273" @default.
• W2023609911 abstract "Formaldehyde (HCHO) may reach living organisms as an exogenous agent or produced within cells. The so-called formaldehydogenic compounds like S-adenosyl-l-methionine, N-hydroxymethyl-l-arginine, 1′-methyl ascorbigen, methanol, E-N-trimethyl lysine and methylamine are special exogenous sources of HCHO. Endogenous HCHO can be formed from hydroxymethyl groups during enzymatic methylation and demethylation processes. HCHO, as a highly reactive compound, is considered to be involved in the induction of apoptosis, consequently in the pathogenesis of atherosclerosis and neurodegenerative processes. The biological action of HCHO is dose-dependent. In vitro studies on tumour cell and endothelial cell cultures showed that HCHO in the concentration of 10.0 mM caused necrotic cell death, 1.0 mM resulted in enhanced apoptosis and reduced mitotic activity, while 0.5 and 0.1 mM enhanced cell proliferation and reduced apoptotic activity. Among formaldehydogenic compounds N-hydroxymethyl-l-arginine, 1′-methyl ascorbigen and the HCHO donor resveratrol may be considered as potential inhibitors of cell proliferation. Endogenous HCHO in plants apparently play a role in regulation of apoptosis and cell proliferation. The genotoxic and carcinogentic effects of HCHO is due to production of DNA—protein cross-links. Low doses of HCHO, reducing apoptotic activity may also accumulate cells with such cross-links. Experimental data point to the possible therapeutic use of methylated lysine residues and methylated arginine residues in the case of neoplasms." @default.
• W2023609911 created "2016-06-24" @default.
• W2023609911 creator A5014648112 @default.
• W2023609911 creator A5083603201 @default.
• W2023609911 date "2010-11-11" @default.
• W2023609911 modified "2023-10-04" @default.
• W2023609911 title "Effect of formaldehyde on cell proliferation and death" @default.
• W2023609911 cites W121053086 @default.
• W2023609911 cites W1240583053 @default.
• W2023609911 cites W135110681 @default.
• W2023609911 cites W1561280690 @default.
• W2023609911 cites W157402533 @default.
• W2023609911 cites W1589415602 @default.
• W2023609911 cites W1967694014 @default.
• W2023609911 cites W1972305402 @default.
• W2023609911 cites W1976160619 @default.
• W2023609911 cites W1980624173 @default.
• W2023609911 cites W1985766537 @default.
• W2023609911 cites W1987157178 @default.
• W2023609911 cites W2000739942 @default.
• W2023609911 cites W2001550789 @default.
• W2023609911 cites W2004127401 @default.
• W2023609911 cites W2007580964 @default.
• W2023609911 cites W2007774805 @default.
• W2023609911 cites W2008941833 @default.
• W2023609911 cites W2012124670 @default.
• W2023609911 cites W2013527164 @default.
• W2023609911 cites W2015704862 @default.
• W2023609911 cites W2019571529 @default.
• W2023609911 cites W2019981961 @default.
• W2023609911 cites W2030764183 @default.
• W2023609911 cites W2031920226 @default.
• W2023609911 cites W2033463592 @default.
• W2023609911 cites W2035841466 @default.
• W2023609911 cites W2036285113 @default.
• W2023609911 cites W2039696546 @default.
• W2023609911 cites W2041683594 @default.
• W2023609911 cites W2044319432 @default.
• W2023609911 cites W2045004798 @default.
• W2023609911 cites W2048873043 @default.
• W2023609911 cites W2049365130 @default.
• W2023609911 cites W2049711947 @default.
• W2023609911 cites W2050435712 @default.
• W2023609911 cites W2054643318 @default.
• W2023609911 cites W2059059097 @default.
• W2023609911 cites W2061368325 @default.
• W2023609911 cites W2061380561 @default.
• W2023609911 cites W2065120356 @default.
• W2023609911 cites W2065621895 @default.
• W2023609911 cites W2069265517 @default.
• W2023609911 cites W2075300608 @default.
• W2023609911 cites W2079383900 @default.
• W2023609911 cites W2084735541 @default.
• W2023609911 cites W2085680374 @default.
• W2023609911 cites W2085946449 @default.
• W2023609911 cites W2090085965 @default.
• W2023609911 cites W2097731514 @default.
• W2023609911 cites W2105413614 @default.
• W2023609911 cites W2110438701 @default.
• W2023609911 cites W2122347701 @default.
• W2023609911 cites W2131241337 @default.
• W2023609911 cites W2133918952 @default.
• W2023609911 cites W2134893734 @default.
• W2023609911 cites W2138511905 @default.
• W2023609911 cites W2142092102 @default.
• W2023609911 cites W2144407051 @default.
• W2023609911 cites W2144808416 @default.
• W2023609911 cites W2149648076 @default.
• W2023609911 cites W2151089147 @default.
• W2023609911 cites W2166946563 @default.
• W2023609911 cites W2169972780 @default.
• W2023609911 cites W2396318334 @default.
• W2023609911 cites W2409287415 @default.
• W2023609911 cites W2416238345 @default.
• W2023609911 cites W2460799992 @default.
• W2023609911 cites W2489457116 @default.
• W2023609911 cites W2589486136 @default.
• W2023609911 cites W4212766227 @default.
• W2023609911 cites W4232757804 @default.
• W2023609911 cites W4232880443 @default.
• W2023609911 cites W4235272168 @default.
• W2023609911 cites W4248361105 @default.
• W2023609911 cites W45123465 @default.
• W2023609911 doi "https://doi.org/10.1042/cbi20100532" @default.
• W2023609911 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21067524" @default.
• W2023609911 hasPublicationYear "2010" @default.
• W2023609911 type Work @default.
• W2023609911 sameAs 2023609911 @default.
• W2023609911 citedByCount "55" @default.
• W2023609911 countsByYear W20236099112012 @default.
• W2023609911 countsByYear W20236099112013 @default.
• W2023609911 countsByYear W20236099112014 @default.
• W2023609911 countsByYear W20236099112015 @default.
• W2023609911 countsByYear W20236099112016 @default.
• W2023609911 countsByYear W20236099112017 @default.
• W2023609911 countsByYear W20236099112018 @default.
• W2023609911 countsByYear W20236099112019 @default.
• W2023609911 countsByYear W20236099112020 @default.

• next