Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023615023> ?p ?o ?g. }
- W2023615023 endingPage "2528" @default.
- W2023615023 startingPage "2519" @default.
- W2023615023 abstract "Drug-eluting stents (DESs) have been associated with adverse clinical effects. Moreover, recent publications have shown that the coating of DESs suffers from defects. The purpose of this contribution is to examine a three-step process for surface modification as a means of improving the durability of DESs. In the first step, 4-(2-bromoethyl)benzenediazonium tetrafluoroborate was electrografted onto a stainless steel (SS) stent. X-ray photoelectron spectroscopy (XPS) of the modified stent confirmed the formation of the organic layer. In the second step, methyl methacrylate was polymerized onto the grafted surface by atom-transfer radical polymerization. XPS, electrochemical impedance spectroscopy, and contact-angle measurements were used to characterize the polymer brushes. The last step involved spray-coating of the stent with a drug-in-polymer matrix [poly(n-butyl methacrylate)/poly(ethylene-co-vinyl acetate) + paclitaxel]. Scanning electron microscopy confirmed the considerably improved durability of the drug-in-polymer matrix. Bare controls showed greater cracking and delamination of the coating than did the two-step modified stents after incubation under physiological (37 degrees C) and accelerated (60 degrees C) conditions. Finally, paclitaxel controlled release from the modified SS DESs was moderate compared with that of nontreated samples. In conclusion, the proposed method significantly improves the durability of drug-in-polymer matrixes on a SS DESs." @default.
- W2023615023 created "2016-06-24" @default.
- W2023615023 creator A5027218012 @default.
- W2023615023 creator A5039912614 @default.
- W2023615023 creator A5051858492 @default.
- W2023615023 creator A5058417111 @default.
- W2023615023 creator A5071902582 @default.
- W2023615023 creator A5081047875 @default.
- W2023615023 creator A5086946641 @default.
- W2023615023 date "2009-10-16" @default.
- W2023615023 modified "2023-10-18" @default.
- W2023615023 title "Poly(methyl methacrylate) Grafting onto Stainless Steel Surfaces: Application to Drug-Eluting Stents" @default.
- W2023615023 cites W1968528328 @default.
- W2023615023 cites W1980566832 @default.
- W2023615023 cites W1983608660 @default.
- W2023615023 cites W1984086008 @default.
- W2023615023 cites W1999946194 @default.
- W2023615023 cites W2001705706 @default.
- W2023615023 cites W2002960896 @default.
- W2023615023 cites W2019518242 @default.
- W2023615023 cites W2020255727 @default.
- W2023615023 cites W2022322901 @default.
- W2023615023 cites W2022461286 @default.
- W2023615023 cites W2029474849 @default.
- W2023615023 cites W2029545466 @default.
- W2023615023 cites W2033708409 @default.
- W2023615023 cites W2049735744 @default.
- W2023615023 cites W2054823440 @default.
- W2023615023 cites W2055905394 @default.
- W2023615023 cites W2065225353 @default.
- W2023615023 cites W2068602449 @default.
- W2023615023 cites W2082951726 @default.
- W2023615023 cites W2083860459 @default.
- W2023615023 cites W2083880166 @default.
- W2023615023 cites W2107663410 @default.
- W2023615023 cites W2127123808 @default.
- W2023615023 cites W2128511994 @default.
- W2023615023 cites W2129769022 @default.
- W2023615023 cites W2135807965 @default.
- W2023615023 cites W2136644516 @default.
- W2023615023 cites W2142286991 @default.
- W2023615023 cites W2153674119 @default.
- W2023615023 cites W2162303835 @default.
- W2023615023 cites W2162321617 @default.
- W2023615023 cites W2171016707 @default.
- W2023615023 cites W2331673407 @default.
- W2023615023 doi "https://doi.org/10.1021/am900465t" @default.
- W2023615023 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20356122" @default.
- W2023615023 hasPublicationYear "2009" @default.
- W2023615023 type Work @default.
- W2023615023 sameAs 2023615023 @default.
- W2023615023 citedByCount "43" @default.
- W2023615023 countsByYear W20236150232012 @default.
- W2023615023 countsByYear W20236150232013 @default.
- W2023615023 countsByYear W20236150232014 @default.
- W2023615023 countsByYear W20236150232015 @default.
- W2023615023 countsByYear W20236150232016 @default.
- W2023615023 countsByYear W20236150232017 @default.
- W2023615023 countsByYear W20236150232018 @default.
- W2023615023 countsByYear W20236150232019 @default.
- W2023615023 countsByYear W20236150232020 @default.
- W2023615023 countsByYear W20236150232022 @default.
- W2023615023 crossrefType "journal-article" @default.
- W2023615023 hasAuthorship W2023615023A5027218012 @default.
- W2023615023 hasAuthorship W2023615023A5039912614 @default.
- W2023615023 hasAuthorship W2023615023A5051858492 @default.
- W2023615023 hasAuthorship W2023615023A5058417111 @default.
- W2023615023 hasAuthorship W2023615023A5071902582 @default.
- W2023615023 hasAuthorship W2023615023A5081047875 @default.
- W2023615023 hasAuthorship W2023615023A5086946641 @default.
- W2023615023 hasConcept C127413603 @default.
- W2023615023 hasConcept C132050475 @default.
- W2023615023 hasConcept C150539798 @default.
- W2023615023 hasConcept C159985019 @default.
- W2023615023 hasConcept C175708663 @default.
- W2023615023 hasConcept C192562407 @default.
- W2023615023 hasConcept C2775937945 @default.
- W2023615023 hasConcept C2777935641 @default.
- W2023615023 hasConcept C2781448156 @default.
- W2023615023 hasConcept C42360764 @default.
- W2023615023 hasConcept C44228677 @default.
- W2023615023 hasConcept C521977710 @default.
- W2023615023 hasConcept C6556556 @default.
- W2023615023 hasConceptScore W2023615023C127413603 @default.
- W2023615023 hasConceptScore W2023615023C132050475 @default.
- W2023615023 hasConceptScore W2023615023C150539798 @default.
- W2023615023 hasConceptScore W2023615023C159985019 @default.
- W2023615023 hasConceptScore W2023615023C175708663 @default.
- W2023615023 hasConceptScore W2023615023C192562407 @default.
- W2023615023 hasConceptScore W2023615023C2775937945 @default.
- W2023615023 hasConceptScore W2023615023C2777935641 @default.
- W2023615023 hasConceptScore W2023615023C2781448156 @default.
- W2023615023 hasConceptScore W2023615023C42360764 @default.
- W2023615023 hasConceptScore W2023615023C44228677 @default.
- W2023615023 hasConceptScore W2023615023C521977710 @default.
- W2023615023 hasConceptScore W2023615023C6556556 @default.
- W2023615023 hasIssue "11" @default.
- W2023615023 hasLocation W20236150231 @default.