Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023615908> ?p ?o ?g. }
- W2023615908 endingPage "398" @default.
- W2023615908 startingPage "385" @default.
- W2023615908 abstract "Mass spectra were acquired for a therapeutic 4-azasteroid (dutasteride), and some related compounds, using various ionization conditions (EI, CI, APCI and ESI) in both positive and negative ion modes. The ionization and fragmentation behavior of the compound dutasteride, its precursors and several analogs is reported. Positive atmospheric pressure chemical ionization (APCI+) and positive electrospray ionization (ESI+) produced distinctive collision-induced dissociation (CID) spectra for the respective [MH]+ ions of dutasteride. The spectral differences are attributed to ion populations having either different structures or different internal energy distributions (as a consequence of the method of ionization). Irrespective of their origin, the protonated molecules undergo interesting fragmentation reactions when collisionally activated. The identity of the major fragmentation products was confirmed by accurate mass measurement. The negative APCI mass spectrum of dutasteride displays extensive dehydrohalogenation, apparently due to the thermal component of the APCI process. Some of the resulting radical anions display remarkable stability toward collisional decomposition. Details of the fragmentation behavior for the negative ion species and their relationship to the positive ion results are discussed." @default.
- W2023615908 created "2016-06-24" @default.
- W2023615908 creator A5029951146 @default.
- W2023615908 creator A5040533768 @default.
- W2023615908 creator A5057608084 @default.
- W2023615908 creator A5081005932 @default.
- W2023615908 date "2001-04-01" @default.
- W2023615908 modified "2023-09-26" @default.
- W2023615908 title "Mass spectral fragmentation reactions of a therapeutic 4-azasteroid and related compounds" @default.
- W2023615908 cites W1928958763 @default.
- W2023615908 cites W1972432987 @default.
- W2023615908 cites W1972588769 @default.
- W2023615908 cites W1974556160 @default.
- W2023615908 cites W1982099397 @default.
- W2023615908 cites W1984427264 @default.
- W2023615908 cites W1985238671 @default.
- W2023615908 cites W1987360951 @default.
- W2023615908 cites W1987817749 @default.
- W2023615908 cites W1988006519 @default.
- W2023615908 cites W1993039489 @default.
- W2023615908 cites W1999458880 @default.
- W2023615908 cites W2000015822 @default.
- W2023615908 cites W2004223088 @default.
- W2023615908 cites W2007100272 @default.
- W2023615908 cites W2008951602 @default.
- W2023615908 cites W2016022652 @default.
- W2023615908 cites W2017768925 @default.
- W2023615908 cites W2019116026 @default.
- W2023615908 cites W2029090463 @default.
- W2023615908 cites W2029977506 @default.
- W2023615908 cites W2037316705 @default.
- W2023615908 cites W2038753129 @default.
- W2023615908 cites W2040308794 @default.
- W2023615908 cites W2041736399 @default.
- W2023615908 cites W2046618616 @default.
- W2023615908 cites W2049133990 @default.
- W2023615908 cites W2052532860 @default.
- W2023615908 cites W2054386217 @default.
- W2023615908 cites W2067583320 @default.
- W2023615908 cites W2068600232 @default.
- W2023615908 cites W2071613600 @default.
- W2023615908 cites W2084711610 @default.
- W2023615908 cites W2094204930 @default.
- W2023615908 cites W2122774630 @default.
- W2023615908 cites W2125735332 @default.
- W2023615908 cites W2130608150 @default.
- W2023615908 cites W2153263734 @default.
- W2023615908 cites W228687515 @default.
- W2023615908 cites W2330095372 @default.
- W2023615908 cites W2950852565 @default.
- W2023615908 cites W4229660009 @default.
- W2023615908 cites W4233167080 @default.
- W2023615908 cites W4233796272 @default.
- W2023615908 doi "https://doi.org/10.1016/s1044-0305(01)00203-3" @default.
- W2023615908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11322185" @default.
- W2023615908 hasPublicationYear "2001" @default.
- W2023615908 type Work @default.
- W2023615908 sameAs 2023615908 @default.
- W2023615908 citedByCount "17" @default.
- W2023615908 countsByYear W20236159082013 @default.
- W2023615908 countsByYear W20236159082019 @default.
- W2023615908 countsByYear W20236159082021 @default.
- W2023615908 countsByYear W20236159082022 @default.
- W2023615908 crossrefType "journal-article" @default.
- W2023615908 hasAuthorship W2023615908A5029951146 @default.
- W2023615908 hasAuthorship W2023615908A5040533768 @default.
- W2023615908 hasAuthorship W2023615908A5057608084 @default.
- W2023615908 hasAuthorship W2023615908A5081005932 @default.
- W2023615908 hasConcept C102931765 @default.
- W2023615908 hasConcept C111919701 @default.
- W2023615908 hasConcept C113196181 @default.
- W2023615908 hasConcept C145148216 @default.
- W2023615908 hasConcept C147789679 @default.
- W2023615908 hasConcept C148065180 @default.
- W2023615908 hasConcept C162356407 @default.
- W2023615908 hasConcept C176107965 @default.
- W2023615908 hasConcept C178790620 @default.
- W2023615908 hasConcept C185592680 @default.
- W2023615908 hasConcept C191015642 @default.
- W2023615908 hasConcept C198291218 @default.
- W2023615908 hasConcept C30095370 @default.
- W2023615908 hasConcept C31827203 @default.
- W2023615908 hasConcept C40325409 @default.
- W2023615908 hasConcept C40684141 @default.
- W2023615908 hasConcept C41008148 @default.
- W2023615908 hasConcept C43617362 @default.
- W2023615908 hasConcept C51884965 @default.
- W2023615908 hasConceptScore W2023615908C102931765 @default.
- W2023615908 hasConceptScore W2023615908C111919701 @default.
- W2023615908 hasConceptScore W2023615908C113196181 @default.
- W2023615908 hasConceptScore W2023615908C145148216 @default.
- W2023615908 hasConceptScore W2023615908C147789679 @default.
- W2023615908 hasConceptScore W2023615908C148065180 @default.
- W2023615908 hasConceptScore W2023615908C162356407 @default.
- W2023615908 hasConceptScore W2023615908C176107965 @default.
- W2023615908 hasConceptScore W2023615908C178790620 @default.
- W2023615908 hasConceptScore W2023615908C185592680 @default.
- W2023615908 hasConceptScore W2023615908C191015642 @default.