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• W2023622402 abstract "Acta PaediatricaVolume 83, Issue s399 p. 21-24 Consequences of growth hormone deficiency in adults, and effects of growth hormone replacement therapy T Rosén, Corresponding Author T Rosén Endocrine Division, Department of Medicine, University of Gothenburg, Gothenburg, SwedenT Rosén, Endocrine Division, Department of Medicine, S-143 45 Gothenburg, SwedenSearch for more papers by this authorG Johannsson, G Johannsson Endocrine Division, Department of Medicine, University of Gothenburg, Gothenburg, SwedenSearch for more papers by this authorB-Å Bengtsson, B-Å Bengtsson Endocrine Division, Department of Medicine, University of Gothenburg, Gothenburg, SwedenSearch for more papers by this author T Rosén, Corresponding Author T Rosén Endocrine Division, Department of Medicine, University of Gothenburg, Gothenburg, SwedenT Rosén, Endocrine Division, Department of Medicine, S-143 45 Gothenburg, SwedenSearch for more papers by this authorG Johannsson, G Johannsson Endocrine Division, Department of Medicine, University of Gothenburg, Gothenburg, SwedenSearch for more papers by this authorB-Å Bengtsson, B-Å Bengtsson Endocrine Division, Department of Medicine, University of Gothenburg, Gothenburg, SwedenSearch for more papers by this author First published: April 1994 https://doi.org/10.1111/j.1651-2227.1994.tb13280.xCitations: 12AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Falkheden T. Pathophysiological studies following hypophysectomy in man. Thesis, University of Gothenburg, 1963. 2 Cuneo RC, Salomon F, McGauley GA, Sönksen PH. The growth hormone deficiency syndrome in adults. Clin Endocrinol (Oxf) 1992; 37: 387–97. 3 Salomon F, Cuneo RC, Hesp R, Sönksen PH. The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. N Engl J Med 1989; 321: 1797–803. 4 Rosén T, Bosaeus I, Tölli J, Lindstedt G, Bengtsson B-Å. Increased body fat and decreased extracellular fluid volume in adults with growth hormone deficiency. Clin Endocrinol (Oxf) 1993; 38: 63–71. 5 Binnerts A, Deurenberg P, Swart GR, Wilson JHP, Lamberts SWJ. Body composition in growth hormone-deficient adults. Am J Clin Nutr 1992; 55: 918–23. 6 Jörgensen JOL, Thuesen L, Ingemann-Hansen T et al. Beneficial effects of growth hormone treatment in GH-deficient adults. Lancet 1989; i: 1221–5. 7 Cuneo RC, Salomon F, Wiles CM, Hesp R, Sönksen PH. Growth hormone treatment in growth hormone deficient adults. I Effects on muscle mass and strength. J Appl Physiol 1991; 70: 688–94. 8 Barnard R, Ng KW, Martin TJ, Waters MJ. Growth hormone (GH) receptors in clonal osteoblast-like cells mediate a mitogenic response to GH. Endocrinology 1991; 128: 1459–64. 9 Bouillon R. Growth hormone and bone. Horm Res 1991; 36 (Suppl 1): 49–55. 10 Kaufman J-M, Taelman P, Vermeulen A, Vandeweghe M. Bone mineral status in growth hormone-deficient males with isolated and multiple pituitary deficiencies of childhood onset. J Clin Endocrinol Metab 1992; 74: 118–23. 11 Elgindy N, Grunditz R, Thorén M, Degerblad M, Sjöberg H-E, Ringertz H. Long term follow-up of metacarpal cortical thickness and bone mineral density in panhypopituitarism. Radiol Diagn 1991; 32: 326–30. 12 Degerblad M, Elgindy N, Hall K, Sjöberg H-E, Thorén M. Potent effect of recombinant growth hormone on bone mineral density and body composition in adults with panhypopituitarism. Acta Endocrinol 1992; 126: 387–93. 13 Hyer SL, Rodin DA, Tobias JH, Leiper A, Nussey SS. Growth hormone deficiency during puberty reduces adult bone mineral density. Arch Dis Child 1992; 67: 1472–4. 14 O'Halloran DJ, Tsatsoulis A, Whitehouse RW, Holmes SJ, Adams JE, Shalet SM. Increased bone density after recombinant human growth hormone (GH) therapy in adults with isolated GH deficiency. J Clin Endocrinol Metab 1993; 76: 1344–8. 15 Wüster CHR, Slenczka E, Ziegler R. Erhöhte Prävalenz von Osteoporose und Arteriosklerose bei konventionell substituierter Hypophysenvorderlappeninsuffizienz: Bedarf einer zusätzlichen Wachstumshormonsubstitution Klin Wochenschr 1991, 69: 769–73. 16 Rosén T, Hansson T, Granhed H, Szücs J, Bengtsson B-Å. Reduced bone mineral content in adult patients with growth hormone deficiency. Acta Endocrinol 1993; 129: 201–6. 17 Cuneo RC, Salomon F, Wiles CM, Hesp R, Sonksen PH. Growth hormone treatment in growth hormone deficient adults. II Effects on exercise performance. J Appl Physiol 1991; 70: 695–700. 18 Whitehead HM, Boreham C, Mcllrath EM et al. Growth hormone treatment of adults with growth hormone deficiency: results of a 13-month placebo controlled cross-over study. Clin Endocrinol 1992; 36: 45–52. 19 Shahi M, Beshyah S, Hackett D, Sharp P, Johnston D, Foale R. Cardiac structure and function in growth hormone deficiency. Br Heart J 1991; 66: 58. 20 Whitehead HM, Gilliland JS, Allen IV, Hadden DR. Growth hormone treatment in adults with growth hormone deficiency: effect on muscle fibre size and proportions. Acta Paediatr Scand 1989; 356(Suppl): 65–7. 21 Bojs G, Falkheden T, Sjögren B. Studies on glomerular filtration rate and renal plasma flow in pituitary insufficiency in man including measurements of the renal extraction of para-aminohippuric acid. Acta Endocrinol 1961; 37: 616–22. 22 Summers VK, Hipkin LJ, Davis JC. Serum lipids in diseases of the pituitary. Metabolism 1967; 12: 1106–13. 23 Merimee TJ, Hollander W, Fineberg SE. Studies of hyperlipidemia in the HGH-deficient state. Metabolism 1972; 21: 1053–61. 24 Rosén T, Edén S, Larsson G, Wilhelmsen L, Bengtsson B-Å. Cardiovascular risk factors in adult patients with growth hormone deficiency. Acta Endocrinol 1993; 129: 195–200. 25 Assman G, Schulte H. Ergebnisse und Folgerungen aus der Prospektiven Cardiovaskulären Münster (PROCAM)-Studie. In: G Assman, ed. Fettstoffwechselstörungen und Koronare Herzkrankheit. Munich : MMV Medizin Verlag, 1988: 97–110. 26 Markussis V, Beshyah SA, Fisher C, Sharp R, Nicolaides AN, Johnston DG. Detection of premature atherosclerosis by high-resolution ultrasonography in symptom-free hypopituitary adults. Lancet 1992; 340: 1188–92. 27 Lehmann ED, Hopkins KD, Weissberger AJ, Gosling RG, Sönksen PH. Aortic distensibility in growth hormone deficient adults. Letter. Lancet 1993; 341: 309. 28 Rosén T, Bengtsson B-Å. Premature mortality due to cardiovascular disease in hypopituitarism. Lancet 1990; 336: 285–8. 29 Salmi J. Endocrine function before and after operation in patients with chromophobe pituitary adenoma. Thesis, University of Helsinki, 1979. 30 McGauley GA. Quality of life assessment before and after growth hormone treatment in adults with growth hormone deficiency. Acta Paediatr Scand Suppl 1989; 356: 70–2. 31 Rosén T, Wirén L, Wilhelmsen L, Wiklund I, Bengtsson B-Å. Decreased psychological well-being in adult patients with growth hormone deficiency. Clin Endocrinol (Oxf) 1994 (in press). 32 Bengtsson B-Å, Edén S, Lönn L et al. Treatment of adults with growth hormone deficiency with recombinant human growth hormone. J Clin Endocrinol Metab 1993; 76: 309–17. 33 Jörgensen JOL, Pedersen SA, Thuesen L et al. Long-term growth hormone treatment in growth hormone deficient adults. Acta Endocrinol 1991; 125: 449–53. Citing Literature Volume83, Issues399April 1994Pages 21-24 ReferencesRelatedInformation" @default.
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