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• W2023633058 abstract "Childhood malignant tumors and their treatment are not well described in the natural history of methylmalonic aciduria (MMA). Here we present a case of hepatoblastoma occurring in the native liver of a 19-month-old male with MMA. His tumor was unresectable at diagnosis and he received neoadjuvant chemotherapy with cisplatin, 5-fluorouracil and vincristine. He developed metabolic acidosis and hyperglycemia during chemotherapy. In addition, he developed anemia, thrombocytopenia and febrile neutropenia. He underwent a combined liver-kidney transplant for local control of his tumor and to treat MMA. He remains in remission more than five years after his transplant. In addition, his transplant has cured his MMA and he is able to tolerate a regular diet without developing metabolic crises. © 2015 Wiley Periodicals, Inc." @default.
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• W2023633058 date "2015-02-18" @default.
• W2023633058 modified "2023-10-12" @default.
• W2023633058 title "Hepatoblastoma in a patient with methylmalonic aciduria" @default.
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• W2023633058 doi "https://doi.org/10.1002/ajmg.a.36925" @default.
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