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- W2023639912 abstract "The effects of 17 β-estradiol benzoate on sexual receptivity, vaginal and pituitary cytology, and uterine growth were studied in spayed rats in order to compare the relative sensitivities of the behavioral and somatic responses to this steroid. The most sensitive measure was the vaginal smear; full cornification followed administration of 0.2 μg of the estrogen per day. The threshold for attainment of normal levels of sexual receptivity was between 0.8 and 1.6 μg/day. Similar dosage was required to reverse completely the changes in adenohypophyses and uteri resulting from ovariectomy. These results demonstrate that apparently normal sexual behavior may be restored in spayed rats by daily administration of “physiological” doses of estrogen in the absence of progesterone treatment." @default.
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- W2023639912 date "1968-03-01" @default.
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- W2023639912 title "Relative thresholds of behavioral and somatic responses to estrogen" @default.
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