Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023641988> ?p ?o ?g. }
- W2023641988 endingPage "10138" @default.
- W2023641988 startingPage "10125" @default.
- W2023641988 abstract "Life on Earth is constantly exposed to natural electromagnetic fields (EMFs), and it is generally accepted that EMFs may exert a variety of effects on biological systems. Particularly, extremely low-frequency electromagnetic fields (EL-EMFs) affect biological processes such as cell development and differentiation; however, the fundamental mechanisms by which EMFs influence these processes remain unclear. Here we show that EMF exposure induces epigenetic changes that promote efficient somatic cell reprogramming to pluripotency. These epigenetic changes resulted from EMF-induced activation of the histone lysine methyltransferase Mll2. Remarkably, an EMF-free system that eliminates Earth’s naturally occurring magnetic field abrogates these epigenetic changes, resulting in a failure to undergo reprogramming. Therefore, our results reveal that EMF directly regulates dynamic epigenetic changes through Mll2, providing an efficient tool for epigenetic reprogramming including the acquisition of pluripotency." @default.
- W2023641988 created "2016-06-24" @default.
- W2023641988 creator A5003098266 @default.
- W2023641988 creator A5022853665 @default.
- W2023641988 creator A5059470294 @default.
- W2023641988 creator A5075325048 @default.
- W2023641988 creator A5083862217 @default.
- W2023641988 creator A5090121681 @default.
- W2023641988 date "2014-10-01" @default.
- W2023641988 modified "2023-10-14" @default.
- W2023641988 title "Electromagnetic Fields Mediate Efficient Cell Reprogramming into a Pluripotent State" @default.
- W2023641988 cites W1798488865 @default.
- W2023641988 cites W1959834892 @default.
- W2023641988 cites W1974773432 @default.
- W2023641988 cites W1978029065 @default.
- W2023641988 cites W1979342340 @default.
- W2023641988 cites W1985600203 @default.
- W2023641988 cites W1989047560 @default.
- W2023641988 cites W1998511189 @default.
- W2023641988 cites W1999391198 @default.
- W2023641988 cites W2000407409 @default.
- W2023641988 cites W2000660997 @default.
- W2023641988 cites W2007427704 @default.
- W2023641988 cites W2016534953 @default.
- W2023641988 cites W2018113993 @default.
- W2023641988 cites W2024119772 @default.
- W2023641988 cites W2029387074 @default.
- W2023641988 cites W2039551265 @default.
- W2023641988 cites W2039795300 @default.
- W2023641988 cites W2047015004 @default.
- W2023641988 cites W2049656714 @default.
- W2023641988 cites W2049888495 @default.
- W2023641988 cites W2052399271 @default.
- W2023641988 cites W2054066197 @default.
- W2023641988 cites W2067481405 @default.
- W2023641988 cites W2071221989 @default.
- W2023641988 cites W2082643520 @default.
- W2023641988 cites W2084471276 @default.
- W2023641988 cites W2095564987 @default.
- W2023641988 cites W2105406038 @default.
- W2023641988 cites W2121237309 @default.
- W2023641988 cites W2125987139 @default.
- W2023641988 cites W2138977668 @default.
- W2023641988 cites W2141856502 @default.
- W2023641988 cites W2147422160 @default.
- W2023641988 cites W2148328303 @default.
- W2023641988 cites W2148571048 @default.
- W2023641988 cites W2151199834 @default.
- W2023641988 cites W2152075067 @default.
- W2023641988 cites W2162410475 @default.
- W2023641988 doi "https://doi.org/10.1021/nn502923s" @default.
- W2023641988 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25248035" @default.
- W2023641988 hasPublicationYear "2014" @default.
- W2023641988 type Work @default.
- W2023641988 sameAs 2023641988 @default.
- W2023641988 citedByCount "58" @default.
- W2023641988 countsByYear W20236419882015 @default.
- W2023641988 countsByYear W20236419882016 @default.
- W2023641988 countsByYear W20236419882017 @default.
- W2023641988 countsByYear W20236419882018 @default.
- W2023641988 countsByYear W20236419882019 @default.
- W2023641988 countsByYear W20236419882020 @default.
- W2023641988 countsByYear W20236419882021 @default.
- W2023641988 countsByYear W20236419882022 @default.
- W2023641988 countsByYear W20236419882023 @default.
- W2023641988 crossrefType "journal-article" @default.
- W2023641988 hasAuthorship W2023641988A5003098266 @default.
- W2023641988 hasAuthorship W2023641988A5022853665 @default.
- W2023641988 hasAuthorship W2023641988A5059470294 @default.
- W2023641988 hasAuthorship W2023641988A5075325048 @default.
- W2023641988 hasAuthorship W2023641988A5083862217 @default.
- W2023641988 hasAuthorship W2023641988A5090121681 @default.
- W2023641988 hasConcept C104317684 @default.
- W2023641988 hasConcept C107459253 @default.
- W2023641988 hasConcept C134305767 @default.
- W2023641988 hasConcept C145103041 @default.
- W2023641988 hasConcept C1491633281 @default.
- W2023641988 hasConcept C150194340 @default.
- W2023641988 hasConcept C179463898 @default.
- W2023641988 hasConcept C190727270 @default.
- W2023641988 hasConcept C41091548 @default.
- W2023641988 hasConcept C54355233 @default.
- W2023641988 hasConcept C64927066 @default.
- W2023641988 hasConcept C77255625 @default.
- W2023641988 hasConcept C86803240 @default.
- W2023641988 hasConcept C95444343 @default.
- W2023641988 hasConceptScore W2023641988C104317684 @default.
- W2023641988 hasConceptScore W2023641988C107459253 @default.
- W2023641988 hasConceptScore W2023641988C134305767 @default.
- W2023641988 hasConceptScore W2023641988C145103041 @default.
- W2023641988 hasConceptScore W2023641988C1491633281 @default.
- W2023641988 hasConceptScore W2023641988C150194340 @default.
- W2023641988 hasConceptScore W2023641988C179463898 @default.
- W2023641988 hasConceptScore W2023641988C190727270 @default.
- W2023641988 hasConceptScore W2023641988C41091548 @default.
- W2023641988 hasConceptScore W2023641988C54355233 @default.
- W2023641988 hasConceptScore W2023641988C64927066 @default.
- W2023641988 hasConceptScore W2023641988C77255625 @default.