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- W2023643279 abstract "The anti-inflammatory effect of erythromycin was investigated using zymosan-induced peritonitis in mice. When mice were given erythromycin 10 mg/kg/day po for 28 days, a marked suppression of inflammatory responses, including the reduced influx of leucocytes, plasma exudation and prostaglandin E2 synthesis, was observed. However, neither a 7-day treatment with erythromycin nor a 28-day treatment with clindamycin suppressed the response. The anti-inflammatory activity induced after a 28-day treatment with erythromycin was comparable to the anti-inflammatory effect conferred by a 2-day treatment with dexamethasone 40μg/mouse/day. Thus, these data confirm previous studies which show that erythromycin can exert an anti-inflammatory effect when used over long periods of time." @default.
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- W2023643279 date "1992-01-01" @default.
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- W2023643279 title "The anti-inflammatory effect of erythromycin in zymosan-induced peritonitis of mice" @default.
- W2023643279 doi "https://doi.org/10.1093/jac/30.3.339" @default.
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