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- W2023645046 abstract "G protein‐coupled receptor kinase 2 (GRK2) plays a key role in determining the rate and extent of G protein‐coupled receptor (GPCR) desensitization and resensitization. Recent data indicate that GRK2 activity, subcellular distribution and expression are tightly regulated. The important physiological function of GRK2 as a modulator of the efficacy of GPCR signal transduction systems is exemplified by its relevance in cardiovascular physiopathology as well as by its emerging role in the regulation of chemokine receptors." @default.
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- W2023645046 date "1998-06-23" @default.
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- W2023645046 title "G protein‐coupled receptor kinase 2 (GRK2): mechanisms of regulation and physiological functions" @default.
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- W2023645046 doi "https://doi.org/10.1016/s0014-5793(98)00495-5" @default.
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