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- W2023645097 abstract "Abstract The possible anticancer mechanisms of chelerythrine (CHE) and its interactions with adenosine were investigated by UV‐visible spectrophotometric and spectrofluorimetric measurements and by thermodynamic calculations. The binding of CHE to adenosine could be characterized by the hypochromic and bathochromic effects in the absorption bands and the quenching of fluorescence intensity. The spectral data were fitted by linear analysis, yielding a binding constant of 8.68×104 L · mol−1 at 25°C of CHE with adenosine, and a van't Hoff enthalpy of 92.8 kJ/mol for the endothermic interactions. In addition, with ΔG=−28.2 kJ/mol and ΔS=406 J/mol · K, the interactions should be entropy‐driven." @default.
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- W2023645097 date "2007-05-01" @default.
- W2023645097 modified "2023-09-23" @default.
- W2023645097 title "A Spectral Study of the Interaction Between Chelerythrine Chloride and Adenosine" @default.
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- W2023645097 doi "https://doi.org/10.1080/00387010701301097" @default.
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