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- W2023647422 abstract "Three new furan derivatives, plakorsins A-C (6-8), together with a new fatty acid, plakortic acid (9), have been isolated from the Taiwanese marine sponge Plakortis simplex in addition to the known metabolites chondrillin (1), 6-epi-chondrillin (2), 2-oxo-2,5-dihydrofuran-5-acetic acid methyl ester (methyl 1,4-epoxy-1-oxo-2-hexenoate) (3), dimethyl beta-ketoadipate (4), and the monomethyl ester of cis,cis-muconic acid (5). The structures of these compounds were established mainly on the basis of spectral data and chemical methods. Biological studies revealed that compound 7 exhibited cytotoxic activity against COLO-250 and KB-16 cells, and compound 1 is active against KB-16 cells." @default.
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- W2023647422 date "2001-02-21" @default.
- W2023647422 modified "2023-10-16" @default.
- W2023647422 title "Three New Furan Derivatives and a New Fatty Acid from a Taiwanese Marine Sponge <i>Plakortis simplex</i>" @default.
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- W2023647422 doi "https://doi.org/10.1021/np000413d" @default.
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