FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2023648599> ?p ?o ?g. }

• W2023648599 endingPage "1421" @default.
• W2023648599 startingPage "1409" @default.
• W2023648599 abstract "Electrospray mass spectrometric studies in native folded forms of several proteins in aqueous solution have been performed in the positive and negative ion modes. The mass spectra of the proteins show peaks corresponding to multiple charge states of the gaseous protein ions. The results have been analyzed using the known crystal structures of these proteins. Crystal structure analysis shows that among the surface exposed residues some are involved in hydrogen-bonding or salt-bridge interactions while some are free. The maximum positive charge state of the gaseous protein ions was directly related to the number of free surface exposed basic groups whereas the maximum negative charge state was related to the number of free surface exposed acidic groups of the proteins. The surface exposed basic groups, which are involved in hydrogen bonding, have lower propensity to contribute to the positive charge of the protein. Similarly, the surface exposed acidic groups involved in salt bridges have lower propensity to contribute to the negative charge of the protein. Analysis of the crystal structure to determine the maximum charge state of protein in the electrospray mass spectrum was also used to interpret the reported mass spectra of several proteins. The results show that both the positive and the negative ion mass spectra of the proteins could be interpreted by simple consideration of the crystal structure of the folded proteins. Moreover, unfolding of the protein was shown to increase the positive charge-state because of the availability of larger number of free basic groups at the surface of the unfolded protein." @default.
• W2023648599 created "2016-06-24" @default.
• W2023648599 creator A5023140436 @default.
• W2023648599 creator A5036393151 @default.
• W2023648599 date "2005-09-01" @default.
• W2023648599 modified "2023-10-10" @default.
• W2023648599 title "Direct correlation of the crystal structure of proteins with the maximum positive and negative charge states of gaseous protein ions produced by electrospray ionization" @default.
• W2023648599 cites W1533734182 @default.
• W2023648599 cites W1965333537 @default.
• W2023648599 cites W1965552870 @default.
• W2023648599 cites W1974378289 @default.
• W2023648599 cites W1975599463 @default.
• W2023648599 cites W1980235240 @default.
• W2023648599 cites W1986560888 @default.
• W2023648599 cites W1989076738 @default.
• W2023648599 cites W1989238978 @default.
• W2023648599 cites W1992174893 @default.
• W2023648599 cites W1992276902 @default.
• W2023648599 cites W1999653979 @default.
• W2023648599 cites W2003020257 @default.
• W2023648599 cites W2003436145 @default.
• W2023648599 cites W2007523183 @default.
• W2023648599 cites W2009247981 @default.
• W2023648599 cites W2012195504 @default.
• W2023648599 cites W2013608848 @default.
• W2023648599 cites W2017926405 @default.
• W2023648599 cites W2020121337 @default.
• W2023648599 cites W2024024256 @default.
• W2023648599 cites W2024412694 @default.
• W2023648599 cites W2028970236 @default.
• W2023648599 cites W2029681303 @default.
• W2023648599 cites W2031094797 @default.
• W2023648599 cites W2031654386 @default.
• W2023648599 cites W2038554914 @default.
• W2023648599 cites W2043295547 @default.
• W2023648599 cites W2045568382 @default.
• W2023648599 cites W2049017264 @default.
• W2023648599 cites W2050416242 @default.
• W2023648599 cites W2057461407 @default.
• W2023648599 cites W2058772134 @default.
• W2023648599 cites W2062546305 @default.
• W2023648599 cites W2063478852 @default.
• W2023648599 cites W2063631807 @default.
• W2023648599 cites W2069102089 @default.
• W2023648599 cites W2069818999 @default.
• W2023648599 cites W2070634705 @default.
• W2023648599 cites W2072770926 @default.
• W2023648599 cites W2073019249 @default.
• W2023648599 cites W2073682446 @default.
• W2023648599 cites W2075726640 @default.
• W2023648599 cites W2079936698 @default.
• W2023648599 cites W2085691308 @default.
• W2023648599 cites W2086306647 @default.
• W2023648599 cites W2088836996 @default.
• W2023648599 cites W2089329467 @default.
• W2023648599 cites W2090989207 @default.
• W2023648599 cites W2094150300 @default.
• W2023648599 cites W2100043909 @default.
• W2023648599 cites W2123218964 @default.
• W2023648599 cites W2132717858 @default.
• W2023648599 cites W2148131811 @default.
• W2023648599 cites W2165192566 @default.
• W2023648599 cites W2166440963 @default.
• W2023648599 cites W2169486723 @default.
• W2023648599 cites W4246335285 @default.
• W2023648599 doi "https://doi.org/10.1016/j.jasms.2005.04.002" @default.
• W2023648599 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16006142" @default.
• W2023648599 hasPublicationYear "2005" @default.
• W2023648599 type Work @default.
• W2023648599 sameAs 2023648599 @default.
• W2023648599 citedByCount "37" @default.
• W2023648599 countsByYear W20236485992012 @default.
• W2023648599 countsByYear W20236485992013 @default.
• W2023648599 countsByYear W20236485992014 @default.
• W2023648599 countsByYear W20236485992015 @default.
• W2023648599 countsByYear W20236485992016 @default.
• W2023648599 countsByYear W20236485992018 @default.
• W2023648599 countsByYear W20236485992019 @default.
• W2023648599 crossrefType "journal-article" @default.
• W2023648599 hasAuthorship W2023648599A5023140436 @default.
• W2023648599 hasAuthorship W2023648599A5036393151 @default.
• W2023648599 hasConcept C104317684 @default.
• W2023648599 hasConcept C112887158 @default.
• W2023648599 hasConcept C113196181 @default.
• W2023648599 hasConcept C115624301 @default.
• W2023648599 hasConcept C143065580 @default.
• W2023648599 hasConcept C145148216 @default.
• W2023648599 hasConcept C147789679 @default.
• W2023648599 hasConcept C162356407 @default.
• W2023648599 hasConcept C178790620 @default.
• W2023648599 hasConcept C185592680 @default.
• W2023648599 hasConcept C194451485 @default.
• W2023648599 hasConcept C199360897 @default.
• W2023648599 hasConcept C2780358262 @default.
• W2023648599 hasConcept C2781285689 @default.
• W2023648599 hasConcept C30765947 @default.
• W2023648599 hasConcept C32909587 @default.
• W2023648599 hasConcept C40684141 @default.

• next